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Gene id |
1017 |
| Gene Summary Protein Summary Gene ontology KEGG pathways Diseases PubMed |
Gene Summary
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Gene Symbol |
CDK2 Gene UCSC Ensembl |
|
Aliases |
CDKN2, p33(CDK2) |
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Gene name |
cyclin dependent kinase 2 |
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Alternate names |
cyclin-dependent kinase 2, cdc2-related protein kinase, cell division protein kinase 2, p33 protein kinase, |
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Gene location |
12q13.2 (55966829: 55972788) Exons: 8 NC_000012.12
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Gene summary(Entrez) |
This gene encodes a member of a family of serine/threonine protein kinases that participate in cell cycle regulation. The encoded protein is the catalytic subunit of the cyclin-dependent protein kinase complex, which regulates progression through the cell
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OMIM |
116953 |
Protein Summary
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| GO accession | Term name | Evidence code | Go category |
|---|
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| Associated diseases |
References |
| Cancer | GAD: 19124506 |
| Asthma | GAD: 21804548 |
| Diabetes | GAD: 18198356 |
| Polycystic ovary syndrome (PCOS) | INFBASE: 19631369 |
| Azoospermia | GAD: 18941885 |
| Aberrant CpGs in Low Motility Sperm | MIK: 21674046 |
| Non-obstructuive azoospermia | MIK: 29373224 |
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| PMID |
Condition |
Mutation |
Ethnicity |
Population details |
Infertility_type |
Associated_genes |
Abstract |
| 29373224 |
Non-obstru
ctuive azo
ospermia
|
c.324G>A in exon 1; c.363T>C in exon 2; c.*570G>A; and c.*1160G>C |
Chinese
|
175 men with id
iopathic NOA wh
o underwent tes
tis biopsy, inc
luding hyposper
matogenesis, ge
rm cell maturat
ion arrest and
Sertoli cell on
ly syndrome
|
Male infertility |
|
Show abstract |
| 21674046 |
Aberrant C
pGs in Low
Motility
Sperm
|
|
|
18
|
Male infertility |
GSE26881
|
Show abstract |
|