• Gene id: 10086

Gene Summary

• Gene Symbol: HHLA1   Gene   UCSC   Ensembl
• Aliases: PLA2L
• Gene name: HERV-H LTR-associating 1
• Alternate names: HERV-H LTR-associating protein 1,
• Gene location: 8q24.22 (132105264: 132061485)     Exons: 16     NC_000008.11

Protein Summary

• Protein general information: C9JL84  
  • Name: HERV H LTR associating protein 1
  • Length: 531  
  • Mass: 58297
• Sequence:

  MLGFLSRGPSMKLCMGLACVLSLWNTVSGIKGEAKKEKGMTFLPTTVSGLREEERKEKGVAFLATTELPARSIDL
  SALNLTELVNGMLSRALKDSKKFFSLLSVTSYSSFAFHKFSVAVYNISNLKTVDPAKFPTRYCYCLNNRTNDLSD
  FTALLVDIIGNSTSYLTEIFKSTSILSVNQSNESDCIFICVMTGKSGRNLSDFWEIEEKYPIINYTFTSGLSGVL
  GAATRGTARTSKPTTKSQKTLPSTSPGHWTQSTPWASALRSSPWTETAAPSETEETLNTGRPPELPARATATWFS
  ASHTLPALATRRVARTQWLTADRQTWASISSVPWAQTISEKKPGGSLWETRSSPPTTAGTEEAMNTTSLLAPAAE
  IMATPGSPSQASPTLGAFTHGTQTPSPTKATAPRYPQTGDLSAEWPFTAGEEPVLVPRPHQVSRCPQPLFKVGAM
  AAAPLTLAIQRLNPCLMELCQFFQQCLCMSQRSPRTEDMRYCLEYYSWFLKNATYICQRVKRVSHSHTLKQKCLE
  NICKSV

• Structural information:
  • Interpro: IPR037643  
  • STRING: ENSP00000407107
• Other Databases: GeneCards:  HHLA1  Malacards:  HHLA1

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0005576	extracellular region	IEA	cellular component
GO:0005576	extracellular region	IEA	cellular component

Diseases

Associated diseases	References
Unexplained infertility	MIK: 25753583

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
25753583	Unexplained infertility			46 (17 fertile men, 29 male patients)	Male infertility	Microarray