• Gene id: 100505741

Gene Summary

• Gene Symbol: SPATA1   Gene   UCSC   Ensembl
• Aliases: SP-2, SPAP1
• Gene name: spermatogenesis associated 1
• Alternate names: spermatogenesis-associated protein 1, sperm-specific protein SP-2,
• Gene location: 1p22.3 (84506300: 84556494)     Exons: 15     NC_000001.11
• OMIM: 611992

Protein Summary

• Protein general information: Q5VX52  
  • Name: Spermatogenesis associated protein 1 (Sperm specific protein SP 2)
  • Length: 459  
  • Mass: 52946
• Sequence:

  MKKDKKRNKIPIDNYPIQTLVNMSLNPSRPSSSELVELHVFYVPEGSWNYKLNTISTEVVNKFISAGFLRVSPQL
  TLRALRERLGEFLGEDAIAEKFLFLKCIGNNLAVVKEKQESELKLKSFAPPYALQPELYLLPVMDHLGNVYSPST
  VILDERQTNNGVNEADGTIHRPISVTLFKEELGRDPSLLENTLKELPNKNQEEAGGKATAEKSQIAKNQIGNSEL
  PGSLEDSNNDCFGTKKSQCLWENEDDTAISRRQDNQTAEKEYITLPDHPSLPCQPVLSSGITDISLLQTEREKII
  KQMKQVKEERRYLERNREELVKTVEKLFEQSKLKRYHAYNGWKKKYLETKKVTASMEEVLTKLREDLELYYKKLL
  MQLEAREIKMRPKNLANITDSKNYLIIQITEVQHAIDQLKRKLDTDKMKLIVEVKMRKQAVSDLRTLKTELAQKK
  KIIHLYNLN

• Structural information:
  • Interpro: IPR039062  IPR031478  
• Other Databases: GeneCards:  SPATA1  Malacards:  SPATA1

Diseases

Associated diseases	References
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)