• Gene id: 100316904

Gene Summary

• Gene Symbol: SAP25   Gene   UCSC   Ensembl
• Gene name: Sin3A associated protein 25
• Alternate names: histone deacetylase complex subunit SAP25, 25 kDa Sin3-associated polypeptide, Sin3 corepressor complex subunit SAP25, Sin3A-associated protein, 25kDa, sin3-associated polypeptide, 25kDa, sin3A-binding protein 25,
• Gene location: 7q22.1 (100573899: 100572227)     Exons: 6     NC_000007.14

Protein Summary

• Protein general information: Q8TEE9  
  • Name: Histone deacetylase complex subunit SAP25 (25 kDa Sin3 associated polypeptide) (Sin3 corepressor complex subunit SAP25)
  • Length: 199  
  • Mass: 20873
• Sequence:

  MTPLAPWDPKYEAKAGPRPVWGANCSSGASFSGRTLCHPSFWPLYEAASGRGLRPVAPATGHWNGQQAPPDAGFP
  VVCCEDVFLSDPLLPRGQRVPLYLSKAPQQMMGSLKLLPPPPIMSARVLPRPSPSRGPSTAWLSGPELIALTGLL
  QMSQGEPRPSSSAVGPPDHTSDPPSPCGSPSSSQGADLSLPQTPDTHCP

• Structural information:
  • Interpro: IPR029163  
  • STRING: ENSP00000481351
• Other Databases: GeneCards:  SAP25  Malacards:  SAP25

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0005634	nucleus	IEA	cellular component
GO:0005737	cytoplasm	IEA	cellular component
GO:0006355	regulation of transcription, DNA-templated	IEA	biological process
GO:0005634	nucleus	IEA	cellular component
GO:0005737	cytoplasm	IEA	cellular component
GO:0005737	cytoplasm	IEA	cellular component
GO:0005634	nucleus	IEA	cellular component

Diseases

Associated diseases	References
Cryptorchidism	MIK: 28606200

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq