• Gene id: 100128731

Gene Summary

• Gene Symbol: OST4   Gene   UCSC   Ensembl
• Gene name: oligosaccharyltransferase complex subunit 4, non-catalytic
• Alternate names: dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4, oligosaccharyltransferase 4 homolog,
• Gene location: 2p23.3 (27071653: 27070471)     Exons: 2     NC_000002.12

Protein Summary

• Protein general information: P0C6T2  
  • Name: Dolichyl diphosphooligosaccharide protein glycosyltransferase subunit 4
  • Length: 37  
  • Mass: 4193
• Sequence:

  MITDVQLAIFANMLGVSLFLLVVLYHYVAVNNPKKQE

• Structural information:
  • Interpro: IPR018943  IPR036330  
  • PDB: 2LAT 6S7O 6S7T
  • PDBsum: 2LAT 6S7O 6S7T
  • STRING: ENSP00000457935
• Other Databases: GeneCards:  OST4  Malacards:  OST4

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0008250	oligosaccharyltransferase complex	IDA	cellular component
GO:0018279	protein N-linked glycosylation via asparagine	IMP	biological process
GO:0005783	endoplasmic reticulum	IEA	cellular component
GO:0016020	membrane	IEA	cellular component
GO:0016021	integral component of membrane	IEA	cellular component
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005789	endoplasmic reticulum membrane	IEA	cellular component
GO:0005783	endoplasmic reticulum	IEA	cellular component
GO:0006486	protein glycosylation	IEA	biological process

Diseases

Associated diseases	References
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)