• Gene id: 9689

Gene Summary

• Gene Symbol: BZW1   Gene   UCSC   Ensembl
• Aliases: BZAP45, Nbla10236
• Gene name: basic leucine zipper and W2 domains 1
• Alternate names: basic leucine zipper and W2 domain-containing protein 1, basic leucine-zipper protein BZAP45, putative protein product of Nbla10236,
• Gene location: 2q33.1 (200811545: 200827337)     Exons: 15     NC_000002.12

Protein Summary

• Protein general information: Q7L1Q6  
  • Name: Basic leucine zipper and W2 domain containing protein 1 (Protein Orf)
  • Length: 419  
  • Mass: 48043
• Sequence:

  MNNQKQQKPTLSGQRFKTRKRDEKERFDPTQFQDCIIQGLTETGTDLEAVAKFLDASGAKLDYRRYAETLFDILV
  AGGMLAPGGTLADDMMRTDVCVFAAQEDLETMQAFAQVFNKLIRRYKYLEKGFEDEVKKLLLFLKGFSESERNKL
  AMLTGVLLANGTLNASILNSLYNENLVKEGVSAAFAVKLFKSWINEKDINAVAASLRKVSMDNRLMELFPANKQS
  VEHFTKYFTEAGLKELSEYVRNQQTIGARKELQKELQEQMSRGDPFKDIILYVKEEMKKNNIPEPVVIGIVWSSV
  MSTVEWNKKEELVAEQAIKHLKQYSPLLAAFTTQGQSELTLLLKIQEYCYDNIHFMKAFQKIVVLFYKAEVLSEE
  PILKWYKDAHVAKGKSVFLEQMKKFVEWLKNAEEESESEAEEGD

• Structural information:
  • Protein Domains: (247..41-)
    (/note="W2-)
    (/evidence="ECO:0000255|PROSITE-ProRule:PRU00695"-)
  • Interpro: IPR016024  IPR016021  IPR003307  
  • Prosite: PS51363
  • STRING: ENSP00000394316
• Other Databases: GeneCards:  BZW1  Malacards:  BZW1

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0005737	cytoplasm	IBA	cellular component
GO:0045296	cadherin binding	HDA	molecular function
GO:0005737	cytoplasm	IDA	cellular component
GO:0005737	cytoplasm	IDA	cellular component
GO:0016020	membrane	HDA	cellular component
GO:0003723	RNA binding	HDA	molecular function
GO:0003723	RNA binding	HDA	molecular function

Diseases

Associated diseases	References
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)