• Gene id: 9678

Gene Summary

• Gene Symbol: PHF14   Gene   UCSC   Ensembl
• Gene name: PHD finger protein 14
• Alternate names: PHD finger protein 14,
• Gene location: 7p21.3 (10973871: 11169617)     Exons: 19     NC_000007.14
• OMIM: 617155

Protein Summary

• Protein general information: O94880  
  • Name: PHD finger protein 14
  • Length: 888  
  • Mass: 100053
• Sequence:

  MDRSSKRRQVKPLAASLLEALDYDSSDDSDFKVGDASDSEGSGNGSEDASKDSGEGSCSDSEENILEEELNEDIK
  VKEEQLKNSAEEEVLSSEKQLIKMEKKEEEENGERPRKKKEKEKEKEKEKEKEKEREKEKEKATVSENVAASAAA
  TTPATSPPAVNTSPSVPTTTTATEEQVSEPKKWNLRRNRPLLDFVSMEELNDMDDYDSEDDNDWRPTVVKRKGRS
  ASQKEGSDGDNEDDEDEGSGSDEDENDEGNDEDHSSPASEGGCKKKKSKVLSRNSADDEELTNDSLTLSQSKSNE
  DSLILEKSQNWSSQKMDHILICCVCLGDNSEDADEIIQCDNCGITVHEGCYGVDGESDSIMSSASENSTEPWFCD
  ACKCGVSPSCELCPNQDGIFKETDAGRWVHIVCALYVPGVAFGDIDKLRPVTLTEMNYSKYGAKECSFCEDPRFA
  RTGVCISCDAGMCRAYFHVTCAQKEGLLSEAAAEEDIADPFFAYCKQHADRLDRKWKRKNYLALQSYCKMSLQER
  EKQLSPEAQARINARLQQYRAKAELARSTRPQAWVPREKLPRPLTSSASAIRKLMRKAELMGISTDIFPVDNSDT
  SSSVDGRRKHKQPALTADFVNYYFERNMRMIQIQENMAEQKNIKDKLENEQEKLHVEYNKLCESLEELQNLNGKL
  RSEGQGIWALLGRITGQKLNIPAILRAPKERKPSKKEGGTQKTSTLPAVLYSCGICKKNHDQHLLLLCDTCKLHY
  HLGCLDPPLTRMPRKTKNSYWQCSECDQAGSSDMEADMAMETLPDGTKRSRRQIKEPVKFVPQDVPPEPKKIPIR
  NTRTRGRKRSFVPEEEKHEERVPRERRQRQSVLQKKPKAEDLRTECATCKGTGDNENLVRYPS

• Structural information:
  • Interpro: IPR034732  IPR019786  IPR011011  IPR001965  IPR019787   IPR013083  
  • Prosite: PS51805 PS01359 PS50016
  • STRING: ENSP00000385795
• Other Databases: GeneCards:  PHF14  Malacards:  PHF14

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0046872	metal ion binding	IEA	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0008285	negative regulation of cell population proliferation	IEA	biological process
GO:2000791	negative regulation of mesenchymal cell proliferation involved in lung development	IEA	biological process
GO:2000584	negative regulation of platelet-derived growth factor receptor-alpha signaling pathway	IEA	biological process
GO:0072201	negative regulation of mesenchymal cell proliferation	IEA	biological process
GO:0048286	lung alveolus development	IEA	biological process
GO:0005634	nucleus	IEA	cellular component
GO:0000122	negative regulation of transcription by RNA polymerase II	IEA	biological process

Diseases

Associated diseases	References
Cryptorchidism	MIK: 28606200

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq