|
Gene id |
9633 |
| Gene Summary Protein Summary Diseases PubMed |
Gene Summary
|
|
Gene Symbol |
TESMIN Gene UCSC Ensembl |
|
Aliases |
CXCDC2, MTL5, MTLT |
|
Gene name |
testis expressed metallothionein like protein |
|
Alternate names |
tesmin, CXC domain containing 2, metallothionein-like 5, testis-specific (tesmin), testis-specific metallothionein-like protein, |
|
Gene location |
11q13.3 (68751563: 68706673) Exons: 11 NC_000009.12
|
|
Gene summary(Entrez) |
Metallothionein proteins are highly conserved low-molecular-weight cysteine-rich proteins that are induced by and bind to heavy metal ions and have no enzymatic activity. They may play a central role in the regulation of cell growth and differentiation an
|
|
OMIM |
604374 |
Protein Summary
|
|
| Associated diseases |
References |
| Associated with multiple stages of spermatogenesis and spermiogenesis, possibly during sperm maturation and/or morphogenesis | MIK: 12606435 |
| Cryptorchidism | MIK: 28606200 |
| Spermatogenic defects | MIK: 31037746 |
| Teratozoospermia | MIK: 17327269 |
|
|
| PMID |
Condition |
Mutation |
Ethnicity |
Population details |
Infertility_type |
Associated_genes |
Abstract |
| 12606435 |
Associated
with mult
iple stage
s of sperm
atogenesis
and sperm
iogenesis,
possibly
during spe
rm maturat
ion and/or
morphogen
esis
|
|
|
|
Male infertility |
|
Show abstract |
| 17327269 |
Teratozoos
permia
|
|
|
19 (6 controls
, 13 cases)
|
Male infertility |
GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
|
Show abstract |
| 28606200 |
Cryptorchi
dism
|
|
|
Monozgotic twin
s (1 control, I
cwith cryptorc
hidism)
|
Male infertility |
MeDIP-Seq
|
Show abstract |
| 31037746 |
Spermatoge
nic defect
s
|
|
|
28 men with az
oospermia
|
Male infertility |
Microarray
|
Show abstract |
| 31037746 |
Spermatoge
nic defect
s
|
|
|
16 (1 control,
15 cases)
|
Male infertility |
GSE6023 analyzed using GEO2R
|
Show abstract |
|