• Gene id: 9552

Gene Summary

• Gene Symbol: SPAG7   Gene   UCSC   Ensembl
• Aliases: ACRP, FSA-1
• Gene name: sperm associated antigen 7
• Alternate names: sperm-associated antigen 7,
• Gene location: 17p13.2 (4967816: 4959225)     Exons: 8     NC_000017.11
• OMIM: 300467

Protein Summary

• Protein general information: O75391  
  • Name: Sperm associated antigen 7
  • Length: 227  
  • Mass: 26034
  • Tissue specificity: Detected in fetal brain. {ECO
• Sequence:

  MADLLGSILSSMEKPPSLGDQETRRKAREQAARLKKLQEQEKQQKVEFRKRMEKEVSDFIQDSGQIKKKFQPMNK
  IERSILHDVVEVAGLTSFSFGEDDDCRYVMIFKKEFAPSDEELDSYRRGEEWDPQKAEEKRKLKELAQRQEEEAA
  QQGPVVVSPASDYKDKYSHLIGKGAAKDAAHMLQANKTYGCVPVANKRDTRSIEEAMNEIRAKKRLRQSGEELPP
  TS

• Structural information:
  • Protein Domains: (46..10-)
    (/note="R3H-)
    (/evidence="ECO:0000255|PROSITE-ProRule:PRU00382"-)
  • Interpro: IPR001374  IPR036867  IPR034068  IPR017330  
  • Prosite: PS51061
  • CDD: cd02636
  • PDB: 2CPM
  • PDBsum: 2CPM
  • STRING: ENSP00000206020
• Other Databases: GeneCards:  SPAG7  Malacards:  SPAG7

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0003676	nucleic acid binding	IEA	molecular function
GO:0005634	nucleus	IEA	cellular component
GO:0005515	protein binding	IPI	molecular function
GO:0005634	nucleus	IEA	cellular component

Diseases

Associated diseases	References
Aberrant CpGs in Low Motility Sperm	MIK: 21674046

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
21674046	Aberrant CpGs in Low Motility Sperm			18	Male infertility	GSE26881