• Gene id: 94086

Gene Summary

• Gene Symbol: HSPB9   Gene   UCSC   Ensembl
• Aliases: CT51
• Gene name: heat shock protein family B (small) member 9
• Alternate names: heat shock protein beta-9, cancer/testis antigen 51, heat shock protein, alpha-crystallin-related, B9, small heat shock protein B9,
• Gene location: 17q21.2 (42122803: 42123351)     Exons: 1     NC_000017.11
• OMIM: 608344

Protein Summary

• Protein general information: Q9BQS6  
  • Name: Heat shock protein beta 9 (HspB9) (Cancer/testis antigen 51) (CT51)
  • Length: 159  
  • Mass: 17486
  • Tissue specificity: Testis specific. {ECO
• Sequence:

  MQRVGNTFSNESRVASRCPSVGLAERNRVATMPVRLLRDSPAAQEDNDHARDGFQMKLDAHGFAPEELVVQVDGQ
  WLMVTGQQQLDVRDPERVSYRMSQKVHRKMLPSNLSPTAMTCCLTPSGQLWVRGQCVALALPEAQTGPSPRLGSL
  GSKASNLTR

• Structural information:
  • Protein Domains: (36..14-)
    (/note="sHSP-)
    (/evidence="ECO:0000255|PROSITE-ProRule:PRU00285"-)
  • Interpro: IPR002068  IPR008978  IPR042940  
  • Prosite: PS01031
  • STRING: ENSP00000458018
• Other Databases: GeneCards:  HSPB9  Malacards:  HSPB9

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0005634	nucleus	IBA	cellular component
GO:0005737	cytoplasm	IBA	cellular component
GO:0005737	cytoplasm	IDA	cellular component
GO:0005634	nucleus	IDA	cellular component
GO:0005634	nucleus	IEA	cellular component
GO:0005737	cytoplasm	IEA	cellular component
GO:0005515	protein binding	IPI	molecular function
GO:0005737	cytoplasm	IEA	cellular component
GO:0005634	nucleus	IEA	cellular component

Diseases

Associated diseases	References
Aberrant CpGs in Low Motility Sperm	MIK: 21674046
Spermatogenic defects	MIK: 31037746
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
21674046	Aberrant CpGs in Low Motility Sperm			18	Male infertility	GSE26881
31037746	Spermatogenic defects			28 men with azoospermia	Male infertility	Microarray
31037746	Spermatogenic defects			16 (1 control, 15 cases)	Male infertility	GSE6023 analyzed using GEO2R