• Gene id: 9236

Gene Summary

• Gene Symbol: CCPG1   Gene   UCSC   Ensembl
• Aliases: CPR8
• Gene name: cell cycle progression 1
• Alternate names: cell cycle progression protein 1, cell cycle progression restoration protein 8,
• Gene location: 15q21.3 (55408509: 55355222)     Exons: 9     NC_000015.10
• OMIM: 611326

Protein Summary

• Protein general information: Q9ULG6  
  • Name: Cell cycle progression protein 1 (Cell cycle progression restoration protein 8)
  • Length: 757  
  • Mass: 87340
• Sequence:

  MSENSSDSDSSCGWTVISHEGSDIEMLNSVTPTDSCEPAPECSSLEQEELQALQIEQGESSQNGTVLMEETAYPA
  LEETSSTIEAEEQKIPEDSIYIGTASDDSDIVTLEPPKLEEIGNQEVVIVEEAQSSEDFNMGSSSSSQYTFCQPE
  TVFSSQPSDDESSSDETSNQPSPAFRRRRARKKTVSASESEDRLVAEQETEPSKELSKRQFSSGLNKCVILALVI
  AISMGFGHFYGTIQIQKRQQLVRKIHEDELNDMKDYLSQCQQEQESFIDYKSLKENLARCWTLTEAEKMSFETQK
  TNLATENQYLRVSLEKEEKALSSLQEELNKLREQIRILEDKGTSTELVKENQKLKQHLEEEKQKKHSFLSQRETL
  LTEAKMLKRELERERLVTTALRGELQQLSGSQLHGKSDSPNVYTEKKEIAILRERLTELERKLTFEQQRSDLWER
  LYVEAKDQNGKQGTDGKKKGGRGSHRAKNKSKETFLGSVKETFDAMKNSTKEFVRHHKEKIKQAKEAVKENLKKF
  SDSVKSTFRHFKDTTKNIFDEKGNKRFGATKEAAEKPRTVFSDYLHPQYKAPTENHHNRGPTMQNDGRKEKPVHF
  KEFRKNTNSKKCSPGHDCRENSHSFRKACSGVFDCAQQESMSLFNTVVNPIRMDEFRQIIQRYMLKELDTFCHWN
  ELDQFINKFFLNGVFIHDQKLFTDFVNDVKDYLRNMKEYEVDNDGVFEKLDEYIYRHFFGHTFSPPYGPRSVYIK
  PCHYSSL

• Structural information:
  • Interpro: IPR033588  
  • STRING: ENSP00000403400
• Other Databases: GeneCards:  CCPG1  Malacards:  CCPG1

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0005515	protein binding	IPI	molecular function
GO:2001106	regulation of Rho guanyl-nucleotide exchange factor activity	IBA	biological process
GO:0016020	membrane	IBA	cellular component
GO:2001106	regulation of Rho guanyl-nucleotide exchange factor activity	IEA	biological process
GO:0016021	integral component of membrane	IEA	cellular component
GO:0007049	cell cycle	IEA	biological process
GO:0016020	membrane	IEA	cellular component
GO:2001106	regulation of Rho guanyl-nucleotide exchange factor activity	IEA	biological process
GO:0045944	positive regulation of transcription by RNA polymerase II	IEA	biological process
GO:0016020	membrane	IEA	cellular component
GO:0045787	positive regulation of cell cycle	IMP	biological process
GO:0008284	positive regulation of cell population proliferation	IMP	biological process
GO:0003674	molecular_function	ND	molecular function

Diseases

Associated diseases	References
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			13 (5 controls, 8 cases)	Male infertility	GSE6967 analyzed by GEO2R (cutoff 1.5 fold)