• Gene id: 91409

Gene Summary

• Gene Symbol: CCDC74B   Gene   UCSC   Ensembl
• Gene name: coiled-coil domain containing 74B
• Alternate names: coiled-coil domain-containing protein 74B,
• Gene location: 2q21.1 (130145111: 130139282)     Exons: 15     NC_000002.12

Protein Summary

• Protein general information: Q96LY2  
  • Name: Coiled coil domain containing protein 74B
  • Length: 380  
  • Mass: 41826
• Sequence:

  MSGAGVAAGTRPPSSPTPGSRRRRQRPSVGVQSLRPQSPQLRQSDPQKRNLDLEKSLQFLQQQHSEMLAKLHEEI
  EHLKRENKDLRYKLIMNQTSQKKDGPSGNHLSRASAPLGARWVCINGVWVEPGGPSPARLKEGSSRTHRPGGKHG
  RLAGGSADTVRSPADSLSTSSFQSVKSISNSGKARPQPGSFNKQDSKADVPQKADLEEEPLLHNSKLDKVPGVQG
  QARKEKAEASNAGAACMGNSQHQGRQMGAAAHPPMILPLPLRKPTTLRQCEVLIRELWNTNLLQTQELQHLKSLL
  EGSQRPQAVPEEASFPRDQEATHFPKVSTKSLSKKCLLLSPPVAERAILPALKQTPKNNFAERQKRLQAMQKRRL
  HRSVL

• Structural information:
  • Interpro: IPR033226  IPR029422  IPR040370  IPR039496  
  • STRING: ENSP00000308873
• Other Databases: GeneCards:  CCDC74B  Malacards:  CCDC74B

Diseases

Associated diseases	References
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)