• Gene id: 9050

Gene Summary

• Gene Symbol: PSTPIP2   Gene   UCSC   Ensembl
• Aliases: MAYP
• Gene name: proline-serine-threonine phosphatase interacting protein 2
• Alternate names: proline-serine-threonine phosphatase-interacting protein 2, PEST phosphatase-interacting protein 2,
• Gene location: tdb7990 (46072326: 45983535)     Exons: 16     NC_000018.10
• OMIM: 618692

Protein Summary

• Protein general information: Q9H939  
  • Name: Proline serine threonine phosphatase interacting protein 2 (PEST phosphatase interacting protein 2)
  • Length: 334  
  • Mass: 38858
• Sequence:

  MTRSLFKGNFWSADILSTIGYDNIIQHLNNGRKNCKEFEDFLKERAAIEERYGKDLLNLSRKKPCGQSEINTLKR
  ALEVFKQQVDNVAQCHIQLAQSLREEARKMEEFREKQKLQRKKTELIMDAIHKQKSLQFKKTMDAKKNYEQKCRD
  KDEAEQAVSRSANLVNPKQQEKLFVKLATSKTAVEDSDKAYMLHIGTLDKVREEWQSEHIKACEAFEAQECERIN
  FFRNALWLHVNQLSQQCVTSDEMYEQVRKSLEMCSIQRDIEYFVNQRKTGQIPPAPIMYENFYSSQKNAVPAGKA
  TGPNLARRGPLPIPKSSPDDPNYSLVDDYSLLYQ

• Structural information:
  • Protein Domains: (4..26-)
    (/note="F-BAR-)
    (/evidence="ECO:0000255|PROSITE-ProRule:PRU01077"-)
  • Interpro: IPR027267  IPR031160  IPR001060  IPR030106  IPR042694  
  • Prosite: PS51741
  • CDD: cd07672
  • STRING: ENSP00000387261
• Other Databases: GeneCards:  PSTPIP2  Malacards:  PSTPIP2

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0008092	cytoskeletal protein binding	IBA	molecular function
GO:0005737	cytoplasm	IBA	cellular component
GO:0005856	cytoskeleton	IBA	cellular component
GO:0005886	plasma membrane	IBA	cellular component
GO:0003779	actin binding	IEA	molecular function
GO:0007010	cytoskeleton organization	IEA	biological process
GO:0016477	cell migration	IEA	biological process
GO:0005737	cytoplasm	IEA	cellular component
GO:0016020	membrane	IEA	cellular component
GO:0005829	cytosol	IEA	cellular component
GO:0016020	membrane	IEA	cellular component
GO:0005856	cytoskeleton	IEA	cellular component
GO:0016020	membrane	IEA	cellular component
GO:0005737	cytoplasm	IEA	cellular component

Diseases

Associated diseases	References
Aberrant CpGs in Low Motility Sperm	MIK: 21674046

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
21674046	Aberrant CpGs in Low Motility Sperm			18	Male infertility	GSE26881