• Gene id: 89944

Gene Summary

• Gene Symbol: GLB1L2   Gene   UCSC   Ensembl
• Aliases: MST114, MSTP114
• Gene name: galactosidase beta 1 like 2
• Alternate names: beta-galactosidase-1-like protein 2,
• Gene location: 11q25 (134331873: 134376323)     Exons: 22     NC_000011.10
• OMIM: 300380

Protein Summary

• Protein general information: Q8IW92  
  • Name: Beta galactosidase 1 like protein 2 (EC 3.2.1. )
  • Length: 636  
  • Mass: 72079
• Sequence:

  MTTWSLRRRPARTLGLLLLVVLGFLVLRRLDWSTLVPLRLRHRQLGLQAKGWNFMLEDSTFWIFGGSIHYFRVPR
  EYWRDRLLKMKACGLNTLTTYVPWNLHEPERGKFDFSGNLDLEAFVLMAAEIGLWVILRPGPYICSEMDLGGLPS
  WLLQDPGMRLRTTYKGFTEAVDLYFDHLMSRVVPLQYKRGGPIIAVQVENEYGSYNKDPAYMPYVKKALEDRGIV
  ELLLTSDNKDGLSKGIVQGVLATINLQSTHELQLLTTFLFNVQGTQPKMVMEYWTGWFDSWGGPHNILDSSEVLK
  TVSAIVDAGSSINLYMFHGGTNFGFMNGAMHFHDYKSDVTSYDYDAVLTEAGDYTAKYMKLRDFFGSISGIPLPP
  PPDLLPKMPYEPLTPVLYLSLWDALKYLGEPIKSEKPINMENLPVNGGNGQSFGYILYETSITSSGILSGHVHDR
  GQVFVNTVSIGFLDYKTTKIAVPLIQGYTVLRILVENRGRVNYGENIDDQRKGLIGNLYLNDSPLKNFRIYSLDM
  KKSFFQRFGLDKWSSLPETPTLPAFFLGSLSISSTPCDTFLKLEGWEKGVVFINGQNLGRYWNIGPQKTLYLPGP
  WLSSGINQVIVFEETMAGPALQFTETPHLGRNQYIK

• Structural information:
  • Interpro: IPR026283  IPR008979  IPR031330  IPR019801  IPR001944   IPR017853  
  • Prosite: PS01182
  • STRING: ENSP00000444628
• Other Databases: GeneCards:  GLB1L2  Malacards:  GLB1L2

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0005773	vacuole	IBA	cellular component
GO:0004565	beta-galactosidase activity	IBA	molecular function
GO:0004565	beta-galactosidase activity	IEA	molecular function
GO:0005975	carbohydrate metabolic process	IEA	biological process
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	IEA	molecular function
GO:0005576	extracellular region	IEA	cellular component
GO:0008152	metabolic process	IEA	biological process
GO:0016787	hydrolase activity	IEA	molecular function
GO:0016798	hydrolase activity, acting on glycosyl bonds	IEA	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005576	extracellular region	IEA	cellular component

Diseases

Associated diseases	References
Unexplained infertility	MIK: 25753583

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
25753583	Unexplained infertility			46 (17 fertile men, 29 male patients)	Male infertility	Microarray