|
Gene id |
8798 |
| Gene Summary Protein Summary Gene ontology Diseases PubMed |
Gene Summary
|
|
Gene Symbol |
DYRK4 Gene UCSC Ensembl |
|
Gene name |
dual specificity tyrosine phosphorylation regulated kinase 4 |
|
Alternate names |
dual specificity tyrosine-phosphorylation-regulated kinase 4, dual specificity tyrosine-(Y)-phosphorylation regulated kinase 4, |
|
Gene location |
12p13.32 (4590071: 4613887) Exons: 13 NC_000011.10
|
|
Gene summary(Entrez) |
This gene encodes an enzyme that belongs to a conserved family of serine/threonine protein kinases. Members of this dual specificity kinase family are thought to function in the regulation of cell differentiation and proliferation, survival, and in develo
|
|
OMIM |
609181 |
Protein Summary
|
|
| GO accession | Term name | Evidence code | Go category |
|---|
|
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| Associated diseases |
References |
| Role in spermiogenesis | MIK: 17292540 |
| Male factor infertility | MIK: 17292540 |
| Aberrant CpGs in Low Motility Sperm | MIK: 21674046 |
| Male infertility | MIK: 17292540 |
| Spermatogenic defects | MIK: 31037746 |
| Teratozoospermia | MIK: 17327269 |
|
|
| PMID |
Condition |
Mutation |
Ethnicity |
Population details |
Infertility_type |
Associated_genes |
Abstract |
| 17292540 |
Role in sp
ermiogenes
is, Male i
nfertility
|
|
|
|
Male infertility |
|
Show abstract |
| 17327269 |
Teratozoos
permia
|
|
|
19 (6 controls
, 13 cases)
|
Male infertility |
GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
|
Show abstract |
| 21674046 |
Aberrant C
pGs in Low
Motility
Sperm
|
|
|
18
|
Male infertility |
GSE26881
|
Show abstract |
| 31037746 |
Spermatoge
nic defect
s
|
|
|
28 men with az
oospermia
|
Male infertility |
Microarray
|
Show abstract |
|