• Gene id: 8715

Gene Summary

• Gene Symbol: NOL4   Gene   UCSC   Ensembl
• Aliases: CT125, HRIHFB2255, NOLP
• Gene name: nucleolar protein 4
• Alternate names: nucleolar protein 4, cancer/testis antigen 125, nucleolar localized protein,
• Gene location: 18q12.1 (34224956: 33851099)     Exons: 22     NC_000018.10
• OMIM: 604797

Protein Summary

• Protein general information: O94818  
  • Name: Nucleolar protein 4 (Nucleolar localized protein)
  • Length: 638  
  • Mass: 71357
  • Tissue specificity: Expressed predominantly in fetal brain, adult brain and testis. {ECO
• Sequence:

  MESERDMYRQFQDWCLRTYGDSGKTKTVTRKKYERIVQLLNGSESSSTDNAKFKFWVKSKGFQLGQPDEVRGGGG
  GAKQVLYVPVKTTDGVGVDEKLSLRRVAVVEDFFDIIYSMHVETGPNGEQIRKHAGQKRTYKAISESYAFLPREA
  VTRFLMSCSECQKRMHLNPDGTDHKDNGKPPTLVTSMIDYNMPITMAYMKHMKLQLLNSQQDEDESSIESDEFDM
  SDSTRMSAVNSDLSSNLEERMQSPQNLHGQQDDDSAAESFNGNETLGHSSIASGGTHSREMGDSNSDGKTGLEQD
  EQPLNLSDSPLSAQLTSEYRIDDHNSNGKNKYKNLLISDLKMEREARENGSKSPAHSYSSYDSGKNESVDRGAED
  LSLNRGDEDEDDHEDHDDSEKVNETDGVEAERLKAFNMFVRLFVDENLDRMVPISKQPKEKIQAIIDSCRRQFPE
  YQERARKRIRTYLKSCRRMKRSGFEMSRPIPSHLTSAVAESILASACESESRNAAKRMRLERQQDESAPADKQCK
  PEATQATYSTSAVPGSQDVLYINGNGTYSYHSYRGLGGGLLNLNDASSSGPTDLSMKRQLATSSGSSSSSNSRPQ
  LSPTEINAVRQLVAGYRESAAFLLRSADELENLILQQN

• Structural information:
  • Interpro: IPR026747  IPR039788  
  • STRING: ENSP00000261592
• Other Databases: GeneCards:  NOL4  Malacards:  NOL4

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0005730	nucleolus	IEA	cellular component
GO:0005634	nucleus	IEA	cellular component
GO:0003723	RNA binding	TAS	molecular function
GO:0005730	nucleolus	TAS	cellular component
GO:0005730	nucleolus	IEA	cellular component

Diseases

Associated diseases	References
Spermatogenic defects	MIK: 31037746

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
31037746	Spermatogenic defects			28 men with azoospermia	Male infertility	Microarray