• Gene id: 85302

Gene Summary

• Gene Symbol: FBF1   Gene   UCSC   Ensembl
• Aliases: Alb, FBF-1
• Gene name: Fas binding factor 1
• Alternate names: fas-binding factor 1, Fas (TNFRSF6) binding factor 1, Fas binding protein 1, albatross, protein albatross,
• Gene location: 17q25.1 (75938231: 75909573)     Exons: 29     NC_000017.11
• OMIM: 603079

Protein Summary

• Protein general information: Q8TES7  
  • Name: Fas binding factor 1 (FBF 1) (Protein albatross)
  • Length: 1133  
  • Mass: 125446
  • Tissue specificity: Present in various epithelial cells (at protein level).
• Sequence:

  MAPKTKKGCKVTLPEKPVKLASHTRDTTGVSQMFPSSKARTKSLLGDDVFSTMAGLEEADAEVSGISEADPQALL
  QAMKDLDGMDADILGLKKSNSAPSKKAAKDPGKGELPNHPKPAGGAIPTKKSLPSPSSSGHQNRRFSSEDLEDPL
  RGLLSYDEGGITKQPPVTQSKTASDKSPSTVRDQGPSIPLTPGDTPIRKKEELLFDDGDDIMATLGFGDSPKAEK
  RQIGDQEGPRPARSTLDELLGRGMATKLLARPGTGEHREFKLDKKYQRPQDSEDMWGDEDFTFGAYQPTVVSSEG
  RQSRRQSVSRFFADSGADPKGEPGSKQSPPMASSPIQPRKGGADWLGLKDEDLDLFPASPTREAHRESSVPVTPS
  VPPPASQHSTPAGLPPSRAKPPTEGAGSPAKASQASKLRASKEEKEDWLSHALSRKKSQGLAREQHAGTSEGLHL
  AGTAGHPPSGSQPLTSTQGLEHAAAGGSSGTTARERPCVRPGVSGSPVTQNHAASALPTGSPKRGTAPGDLSATE
  PATCFPSTQKPTEPSVPVQPLLPESLARSLLPSTEYQKQLLAAQVQLQCSPAELQAELLHSQARLAELEAQVRKL
  ELERAQHELLLGSLQQQHQADLELIESAHRSRIKVLETSYQQREERLRRENEELSARYLSQCQEAEQARAELTAQ
  HQRRLAAIAQEKDQEMERLRELQRASILDMRRDHEEQLQRLKLLKDREVDAATSATSHTRSLNSIIHQMEKFSSS
  LHELSSRVEASHLTTSQERELGIRQRDEQLRALQERLGQQQRDMEEERSRQQEVIGKMEARLNEQSRLLEQERWR
  VTAEQSKAESMQRALEEQRKVTAQQMAMERAELERAKSALLEEQKSVMLKCGEERRRLAAEWAEFSAQQKLSKER
  AEREAERALQVDTQREGTLISLAKQAELKIRASELRAEEKQLAAERAALEQERQELRLEKERINATALRVKLRAE
  EVESMSKVASEKYEEGERALREAQQVQAEQQARLQAVQQQQERLRKQEQHMHQEHLSLAQQRLQLDRARQDLPSS
  LVGLFPRAQGPAASSQSALMPPAPTTRWCSQPPTGLDPSPLHLHARLALLRHMAEQDRDFLENEQFFLETLKKGS
  YNLTSHSA

• Structural information:
  • Interpro: IPR033561  
  • STRING: ENSP00000324292
• Other Databases: GeneCards:  FBF1  Malacards:  FBF1

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0036064	ciliary basal body	IBA	cellular component
GO:0060271	cilium assembly	IBA	biological process
GO:0005814	centriole	IBA	cellular component
GO:0043296	apical junction complex	IDA	colocalizes with
GO:0045095	keratin filament	IDA	colocalizes with
GO:0005814	centriole	IDA	cellular component
GO:0000922	spindle pole	IDA	cellular component
GO:0090162	establishment of epithelial cell polarity	IMP	biological process
GO:0043297	apical junction assembly	IMP	biological process
GO:0060271	cilium assembly	IMP	biological process
GO:0005515	protein binding	IPI	molecular function
GO:0060271	cilium assembly	IEA	biological process
GO:0090162	establishment of epithelial cell polarity	IEA	biological process
GO:0097539	ciliary transition fiber	IEA	cellular component
GO:0030030	cell projection organization	IEA	biological process
GO:0030054	cell junction	IEA	cellular component
GO:0005856	cytoskeleton	IEA	cellular component
GO:0005737	cytoplasm	IEA	cellular component
GO:0097539	ciliary transition fiber	IDA	cellular component
GO:0060271	cilium assembly	IMP	biological process
GO:0005829	cytosol	TAS	cellular component
GO:0005829	cytosol	TAS	cellular component
GO:0005829	cytosol	TAS	cellular component
GO:0005829	cytosol	TAS	cellular component
GO:0005829	cytosol	TAS	cellular component
GO:0005829	cytosol	TAS	cellular component
GO:0005829	cytosol	TAS	cellular component
GO:0097711	ciliary basal body-plasma membrane docking	TAS	biological process
GO:0005814	centriole	IEA	cellular component
GO:0030054	cell junction	IEA	cellular component
GO:0005814	centriole	IEA	cellular component
GO:0000922	spindle pole	IEA	cellular component
GO:0005813	centrosome	IDA	cellular component

Diseases

Associated diseases	References
Cryptorchidism	MIK: 28606200

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq