• Gene id: 85002

Gene Summary

• Gene Symbol: FAM86B1   Gene   UCSC   Ensembl
• Gene name: family with sequence similarity 86 member B1
• Alternate names: putative protein N-methyltransferase FAM86B1, protein FAM86B1,
• Gene location: 8p23.1 (12195435: 12182105)     Exons: 22     NC_000008.11
• OMIM: 616122

Protein Summary

• Protein general information: Q8N7N1  
  • Name: Putative protein N methyltransferase FAM86B1 (EC 2.1.1. )
  • Length: 296  
  • Mass: 32865
• Sequence:

  MAPEENAGTELLLQGFERRFLAVRTLRSFPWQSLEAKLRDSSDSELLRDILQKTVRHPVCVKHPPSVKYAWCFLS
  ELIKKSSGGSVTLSKSTAIISHGTTGLVTWDAALYLAEWAIENPAAFINRTVLELGSGAGLTGLAICKMCRPRAY
  IFSDPHSRVLEQLRGNVLLNGLSLEADITGNLDSPRVTVAQLDWDVAMVHQLSAFQPDVVIAADVLYCPEAIVSL
  VGVLQRLAACREHKRAPEVYVAFTVRNPETCQLFTTELGRDGIRWEAEAHHDQKLFPYGEHLEMAMLNLTL

• Structural information:
  • Interpro: IPR029426  IPR019410  IPR029063  
  • STRING: ENSP00000407067
• Other Databases: GeneCards:  FAM86B1  Malacards:  FAM86B1

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0005829	cytosol	IBA	cellular component
GO:0032259	methylation	IBA	biological process
GO:0008168	methyltransferase activity	IBA	molecular function
GO:0016740	transferase activity	IEA	molecular function
GO:0032259	methylation	IEA	biological process
GO:0008168	methyltransferase activity	IEA	molecular function

Diseases

Associated diseases	References
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			13 (5 controls, 8 cases)	Male infertility	GSE6967 analyzed by GEO2R (cutoff 1.5 fold)