• Gene id: 84954

Gene Summary

• Gene Symbol: MPND   Gene   UCSC   Ensembl
• Gene name: MPN domain containing
• Alternate names: MPN domain-containing protein,
• Gene location: 19p13.3 (4343526: 4360085)     Exons: 13     NC_000019.10
• OMIM: 611340

Protein Summary

• Protein general information: Q8N594  
  • Name: MPN domain containing protein (EC 3.4. . )
  • Length: 471  
  • Mass: 50662
• Sequence:

  MAAPEPLSPAGGAGEEAPEEDEDEAEAEDPERPNAGAGGGRSGGGGSSVSGGGGGGGAGAGGCGGPGGALTRRAV
  TLRVLLKDALLEPGAGVLSIYYLGKKFLGDLQPDGRIMWQETGQTFNSPSAWATHCKKLVNPAKKSGCGWASVKY
  KGQKLDKYKATWLRLHQLHTPATAADESPASEGEEEELLMEEEEEDVLAGVSAEDKSRRPLGKSPSEPAHPEATT
  PGKRVDSKIRVPVRYCMLGSRDLARNPHTLVEVTSFAAINKFQPFNVAVSSNVLFLLDFHSHLTRSEVVGYLGGR
  WDVNSQMLTVLRAFPCRSRLGDAETAAAIEEEIYQSLFLRGLSLVGWYHSHPHSPALPSLQDIDAQMDYQLRLQG
  SSNGFQPCLALLCSPYYSGNPGPESKISPFWVMPPPEMLLVEFYKGSPDLVRLQEPWSQEHTYLDKLKISLASRT
  PKDQSLCHVLEQVCGVLKQGS

• Structural information:
  • Protein Domains: (71..16-)
    (/note="RAMA-)
    (/evidence="ECO:0000255-)
    (272..40-)
    (/note="MPN-)
    (/evidence="ECO:0000255|PROSITE-ProRule:PRU01182"-)
  • Interpro: IPR000555  IPR037518  IPR040843  
  • Prosite: PS50249
  • STRING: ENSP00000471735
• Other Databases: GeneCards:  MPND  Malacards:  MPND

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0016514	SWI/SNF complex	IBA	cellular component
GO:0016787	hydrolase activity	IEA	molecular function
GO:0008233	peptidase activity	IEA	molecular function
GO:0006508	proteolysis	IEA	biological process
GO:0046872	metal ion binding	IEA	molecular function
GO:0008237	metallopeptidase activity	IEA	molecular function

Diseases

Associated diseases	References
Cryptorchidism	MIK: 28606200

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq