• Gene id: 84946

Gene Summary

• Gene Symbol: LTV1   Gene   UCSC   Ensembl
• Aliases: C6orf93, dJ468K18.4
• Gene name: LTV1 ribosome biogenesis factor
• Alternate names: protein LTV1 homolog, LTV1 homolog,
• Gene location: 6q24.2 (143843272: 143863811)     Exons: 11     NC_000006.12
• OMIM: 602632

Protein Summary

• Protein general information: Q96GA3  
  • Name: Protein LTV1 homolog
  • Length: 475  
  • Mass: 54855
• Sequence:

  MPHRKKKPFIEKKKAVSFHLVHRSQRDPLAADESAPQRVLLPTQKIDNEERRAEQRKYGVFFDDDYDYLQHLKEP
  SGPSELIPSSTFSAHNRREEKEETLVIPSTGIKLPSSVFASEFEEDVGLLNKAAPVSGPRLDFDPDIVAALDDDF
  DFDDPDNLLEDDFILQANKATGEEEGMDIQKSENEDDSEWEDVDDEKGDSNDDYDSAGLLSDEDCMSVPGKTHRA
  IADHLFWSEETKSRFTEYSMTSSVMRRNEQLTLHDERFEKFYEQYDDDEIGALDNAELEGSIQVDSNRLQEVLND
  YYKEKAENCVKLNTLEPLEDQDLPMNELDESEEEEMITVVLEEAKEKWDCESICSTYSNLYNHPQLIKYQPKPKQ
  IRISSKTGIPLNVLPKKGLTAKQTERIQMINGSDLPKVSTQPRSKNESKEDKRARKQAIKEERKERRVEKKANKL
  AFKLEKRRQEKELLNLKKNVEGLKL

• Structural information:
  • Interpro: IPR007307  
  • PDB: 6G18 6G4S 6G4W 6G51 6G53
  • PDBsum: 6G18 6G4S 6G4W 6G51 6G53
  • STRING: ENSP00000356548
• Other Databases: GeneCards:  LTV1  Malacards:  LTV1

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0005634	nucleus	IBA	cellular component
GO:0030688	preribosome, small subunit precursor	IBA	cellular component
GO:0000056	ribosomal small subunit export from nucleus	IBA	biological process
GO:0005829	cytosol	IBA	cellular component
GO:0042274	ribosomal small subunit biogenesis	IBA	biological process
GO:0042274	ribosomal small subunit biogenesis	IEA	biological process
GO:0005654	nucleoplasm	TAS	cellular component
GO:0005829	cytosol	TAS	cellular component
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005654	nucleoplasm	IDA	cellular component
GO:0005829	cytosol	IDA	cellular component

Diseases

Associated diseases	References
Aberrant CpGs in Low Motility Sperm	MIK: 21674046

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
21674046	Aberrant CpGs in Low Motility Sperm			18	Male infertility	GSE26881