• Gene id: 84919

Gene Summary

• Gene Symbol: PPP1R15B   Gene   UCSC   Ensembl
• Aliases: CREP, MSSGM2
• Gene name: protein phosphatase 1 regulatory subunit 15B
• Alternate names: protein phosphatase 1 regulatory subunit 15B, protein phosphatase 1, regulatory (inhibitor) subunit 15B,
• Gene location: 1q32.1 (204412453: 204398683)     Exons: 4     NC_000001.11
• Gene summary(Entrez): This gene encodes a protein phosphatase I-interacting protein that promotes the dephosphorylation of eukaryotic translation initiation factor 2A to regulate translation under conditions of cellular stress. The transcribed messenger RNA contains two upstre
• OMIM: 613257

Diseases

Associated diseases	References
Microcephaly, short stature, and impaired glucose metabolism	KEGG:H01923
Microcephaly, short stature, and impaired glucose metabolism	KEGG:H01923
Aberrant CpGs in Low Motility Sperm	MIK: 21674046
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
21674046	Aberrant CpGs in Low Motility Sperm			18	Male infertility	GSE26881