• Gene id: 84680

Gene Summary

• Gene Symbol: ACCS   Gene   UCSC   Ensembl
• Aliases: ACS, PHACS
• Gene name: 1-aminocyclopropane-1-carboxylate synthase homolog (inactive)
• Alternate names: 1-aminocyclopropane-1-carboxylate synthase-like protein 1, 1-aminocyclopropane-1-carboxylate synthase-like protein (non-functional) isoform 1, 1-aminocyclopropane-1-carboxylate synthase-like protein (non-functional) isoform 2, 1-aminocyclopropane-1-carboxyla,
• Gene location: 11p11.2 (44066117: 44084236)     Exons: 20     NC_000011.10

Protein Summary

• Protein general information: Q96QU6  
  • Name: 1 aminocyclopropane 1 carboxylate synthase like protein 1 (ACC synthase like protein 1)
  • Length: 501  
  • Mass: 57324
• Sequence:

  MFTLPQKDFRAPTTCLGPTCMQDLGSSHGEDLEGECSRKLDQKLPELRGVGDPAMISSDTSYLSSRGRMIKWFWD
  SAEEGYRTYHMDEYDEDKNPSGIINLGTSENKLCFDLLSWRLSQRDMQRVEPSLLQYADWRGHLFLREEVAKFLS
  FYCKSPVPLRPENVVVLNGGASLFSALATVLCEAGEAFLIPTPYYGAITQHVCLYGNIRLAYVYLDSEVTGLDTR
  PFQLTVEKLEMALREAHSEGVKVKGLILISPQNPLGDVYSPEELQEYLVFAKRHRLHVIVDEVYMLSVFEKSVGY
  RSVLSLERLPDPQRTHVMWATSKDFGMSGLRFGTLYTENQDVATAVASLCRYHGLSGLVQYQMAQLLRDRDWINQ
  VYLPENHARLKAAHTYVSEELRALGIPFLSRGAGFFIWVDLRKYLPKGTFEEEMLLWRRFLDNKVLLSFGKAFEC
  KEPGWFRFVFSDQVHRLCLGMQRVQQVLAGKSQVAEDPRPSQSQEPSDQRR

• Structural information:
  • Interpro: IPR004839  IPR015424  IPR015422  IPR015421  
  • STRING: ENSP00000263776
• Other Databases: GeneCards:  ACCS  Malacards:  ACCS

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0009058	biosynthetic process	IEA	biological process
GO:0030170	pyridoxal phosphate binding	IEA	molecular function
GO:0003824	catalytic activity	IEA	molecular function
GO:0042802	identical protein binding	IPI	molecular function
GO:0042802	identical protein binding	IPI	molecular function
GO:0042802	identical protein binding	IPI	molecular function
GO:0042802	identical protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0042218	1-aminocyclopropane-1-carboxylate biosynthetic process	IEA	biological process
GO:0016847	1-aminocyclopropane-1-carboxylate synthase activity	IDA	NOT|molecular function
GO:0030170	pyridoxal phosphate binding	NAS	molecular function

Diseases

Associated diseases	References
Aberrant CpGs in Low Motility Sperm	MIK: 21674046
Spermatogenic defects	MIK: 31037746

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
21674046	Aberrant CpGs in Low Motility Sperm			18	Male infertility	GSE26881
31037746	Spermatogenic defects			28 men with azoospermia	Male infertility	Microarray