• Gene id: 84517

Gene Summary

• Gene Symbol: ACTRT3   Gene   UCSC   Ensembl
• Aliases: ARP-T3, ARPM1
• Gene name: actin related protein T3
• Alternate names: actin-related protein T3, actin-related protein M1,
• Gene location: 3q26.2 (169769560: 169766920)     Exons: 2     NC_000003.12
• OMIM: 608534

Protein Summary

• Protein general information: Q9BYD9  
  • Name: Actin related protein T3 (ARP T3) (Actin related protein M1)
  • Length: 372  
  • Mass: 41008
  • Tissue specificity: Ubiquitously expressed. {ECO
• Sequence:

  MNHCQLPVVIDNGSGMIKAGVAGCREPQFIYPNIIGRAKGQSRAAQGGLELCVGDQAQDWRSSLFISYPVERGLI
  TSWEDMEIMWKHIYDYNLKLKPCDGPVLITEPALNPLANRQQITEMFFEHLGVPAFYMSIQAVLALFAAGFTTGL
  VLNSGAGVTQSVPIFEGYCLPHGVQQLDLAGLDLTNYLMVLMKNHGIMLLSASDRKIVEDIKESFCYVAMNYEEE
  MAKKPDCLEKVYQLPDGKVIQLHDQLFSCPEALFSPCHMNLEAPGIDKICFSSIMKCDTGLRNSFFSNIILAGGS
  TSFPGLDKRLVKDIAKVAPANTAVQVIAPPERKISVWMGGSILASLSAFQDMWITAAEFKEVGPNIVHQRCF

• Structural information:
  • Interpro: IPR004000  IPR020902  IPR030068  
  • Prosite: PS01132
  • STRING: ENSP00000333037
• Other Databases: GeneCards:  ACTRT3  Malacards:  ACTRT3

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0015629	actin cytoskeleton	IBA	cellular component
GO:0005634	nucleus	IBA	cellular component
GO:0005634	nucleus	IEA	cellular component
GO:0005856	cytoskeleton	IEA	cellular component
GO:0005737	cytoplasm	IEA	cellular component
GO:0001673	male germ cell nucleus	IEA	cellular component
GO:0005737	cytoplasm	IEA	cellular component
GO:0005634	nucleus	IEA	cellular component
GO:0005856	cytoskeleton	IEA	cellular component

Diseases

Associated diseases	References
Spermatogenic defects	MIK: 31037746
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
31037746	Spermatogenic defects			28 men with azoospermia	Male infertility	Microarray
31037746	Spermatogenic defects			16 (1 control, 15 cases)	Male infertility	GSE6023 analyzed using GEO2R