• Gene id: 84240

Gene Summary

• Gene Symbol: ZCCHC9   Gene   UCSC   Ensembl
• Aliases: PPP1R41
• Gene name: zinc finger CCHC-type containing 9
• Alternate names: zinc finger CCHC domain-containing protein 9, protein phosphatase 1, regulatory subunit 41, zinc finger, CCHC domain containing 9,
• Gene location: 5q14.1 (81301582: 81313296)     Exons: 6     NC_000005.10
• OMIM: 603346

Protein Summary

• Protein general information: Q8N567  
  • Name: Zinc finger CCHC domain containing protein 9
  • Length: 271  
  • Mass: 30477
• Sequence:

  MTRWARVSTTYNKRPLPATSWEDMKKGSFEGTSQNLPKRKQLEANRLSLKNDAPQAKHKKNKKKKEYLNEDVNGF
  MEYLRQNSQMVHNGQIIATDSEEVREEIAVALKKDSRREGRRLKRQAAKKNAMVCFHCRKPGHGIADCPAALENQ
  DMGTGICYRCGSTEHEITKCKAKVDPALGEFPFAKCFVCGEMGHLSRSCPDNPKGLYADGGGCKLCGSVEHLKKD
  CPESQNSERMVTVGRWAKGMSADYEEILDVPKPQKPKTKIPKVVNF

• Structural information:
  • Interpro: IPR042246  IPR001878  IPR036875  
  • Prosite: PS50158
  • STRING: ENSP00000254037
• Other Databases: GeneCards:  ZCCHC9  Malacards:  ZCCHC9

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0010923	negative regulation of phosphatase activity	IBA	biological process
GO:0010923	negative regulation of phosphatase activity	IDA	biological process
GO:0008270	zinc ion binding	IEA	molecular function
GO:0003676	nucleic acid binding	IEA	molecular function
GO:0046872	metal ion binding	IEA	molecular function
GO:0005634	nucleus	IEA	cellular component
GO:0005730	nucleolus	IEA	cellular component
GO:0005634	nucleus	IEA	cellular component
GO:0005654	nucleoplasm	IDA	cellular component
GO:0005730	nucleolus	IDA	cellular component
GO:0003723	RNA binding	HDA	molecular function

Diseases

Associated diseases	References
Aberrant CpGs in Low Motility Sperm	MIK: 21674046
Cryptorchidism	MIK: 28606200

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
21674046	Aberrant CpGs in Low Motility Sperm			18	Male infertility	GSE26881
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq