• Gene id: 84229

Gene Summary

• Gene Symbol: DRC7   Gene   UCSC   Ensembl
• Aliases: C16orf50, CCDC135, CFAP50, FAP50
• Gene name: dynein regulatory complex subunit 7
• Alternate names: dynein regulatory complex subunit 7, coiled-coil domain containing 135, coiled-coil domain-containing protein 135, coiled-coil domain-containing protein lobo homolog,
• Gene location: 16q21 (57694805: 57731804)     Exons: 19     NC_000017.11
• OMIM: 0

Diseases

Associated diseases	References
May play definite roles regulating differentiation of germ cells during spermatogenesis, particularly during meiosis and spermiogenesis	MIK: 16804880
Aberrant CpGs in Low Motility Sperm	MIK: 21674046
Cryptorchidism	MIK: 28606200
May play definite roles regulating differentiation of germ cells during spermatogenesis, particularly during meiosis and spermiogenesis	MIK: 16804880
Non obstructive azoospermia	MIK: 24012201
Non obstructive azoospermia, Sertoli cell only syndrome	MIK: 23869807
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
16804880	May play definite roles regulating differentiation of germ cells during spermatogenesis, particularly during meiosis and spermiogenesis				Male infertility
24012201	Non obstructive azoospermia			31 (4 controls, 27 cases)	Male infertility	GSE45885 analyzed by GEO2R (cutoff 1.5 fold)
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
23869807	Non obstructive azoospermia, Sertoli cell only syndrome			20 (4 controls, 16 cases)	Male infertility	GSE45887 analyzed by GEO2R (cutoff 1.5 fold)
21674046	Aberrant CpGs in Low Motility Sperm			18	Male infertility	GSE26881
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq