• Gene id: 84138

Gene Summary

• Gene Symbol: SLC7A6OS   Gene   UCSC   Ensembl
• Aliases: Iwr1
• Gene name: solute carrier family 7 member 6 opposite strand
• Alternate names: probable RNA polymerase II nuclear localization protein SLC7A6OS, ADAMS proteinase-related protein, protein SLC7A6OS, solute carrier family 7 member 6 opposite strand transcript,
• Gene location: 16q22.1 (68310947: 68298033)     Exons: 5     NC_000016.10
• OMIM: 0

Protein Summary

• Protein general information: Q96CW6  
  • Name: Probable RNA polymerase II nuclear localization protein SLC7A6OS (ADAMS proteinase related protein) (Solute carrier family 7 member 6 opposite strand transcript)
  • Length: 309  
  • Mass: 35028
• Sequence:

  MEAARTAVLRVKRKRSAEPAEALVLACKRLRSDAVESAAQKTSEGLERAAENNVFHLVATVCSQEEPVQPLLREV
  LRPSRDSQQRVRRNLRASAREVRQEGRYRVLSSRRSLGTTSSGQESEYTPGNPEAAGNSGFQLLDLVHEEGEPEA
  ASAGSCKTSDPDVILCNSVELIRERLTVSEDGPGVRRQEEQKHDDYVYDIYYLETATPGWIENILSVQPYSQEWE
  LVNDDQEPEDIYDDEDDENSENNWRNEYPEEESSDGDEDSRGSADYNSLSEEERGSSRQRMWSKYPLDVQKEFGY
  DSPHDLDSD

• Structural information:
  • Interpro: IPR040218  IPR013883  
  • STRING: ENSP00000263997
• Other Databases: GeneCards:  SLC7A6OS  Malacards:  SLC7A6OS

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0032502	developmental process	IBA	biological process
GO:0015031	protein transport	IEA	biological process
GO:0005737	cytoplasm	IEA	cellular component
GO:0005634	nucleus	IEA	cellular component
GO:0002244	hematopoietic progenitor cell differentiation	IEA	biological process
GO:0005634	nucleus	IEA	cellular component
GO:0005737	cytoplasm	IEA	cellular component

Diseases

Associated diseases	References
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)