|
Gene id |
8409 |
| Gene Summary Protein Summary Gene ontology Diseases PubMed |
Gene Summary
|
|
Gene Symbol |
UXT Gene UCSC Ensembl |
|
Aliases |
ART-27, STAP1 |
|
Gene name |
ubiquitously expressed prefoldin like chaperone |
|
Alternate names |
protein UXT, SKP2-associated alpha PFD 1, androgen receptor trapped clone 27 protein, ubiquitously expressed transcript protein, |
|
Gene location |
Xp11.23 (47659179: 47651791) Exons: 7 NC_000014.9
|
|
Gene summary(Entrez) |
The protein encoded by this gene functions as a cofactor that modulates androgen receptor-dependent transcription, and also plays a critical role in tumor necrosis factor-induced apoptosis. Expression of this gene may play a role in tumorigenesis. Alterna
|
|
OMIM |
300234 |
Protein Summary
|
|
| GO accession | Term name | Evidence code | Go category |
|---|
|
|
| Associated diseases |
References |
| Spermatogenesis defects | MIK: 29649254 |
| Aberrant CpGs in Low Motility Sperm | MIK: 21674046 |
| Spermatogenetic defects, Male infertility | MIK: 29649254 |
| Teratozoospermia | MIK: 17327269 |
| Unexplained infertility | MIK: 25753583 |
|
|
| PMID |
Condition |
Mutation |
Ethnicity |
Population details |
Infertility_type |
Associated_genes |
Abstract |
| 29649254 |
Spermatoge
netic defe
cts, Male
infertilit
y
|
|
|
|
Male infertility |
|
Show abstract |
| 17327269 |
Teratozoos
permia
|
|
|
13 (5 controls,
8 cases)
|
Male infertility |
GSE6967 analyzed by GEO2R (cutoff 1.5 fold)
|
Show abstract |
| 21674046 |
Aberrant C
pGs in Low
Motility
Sperm
|
|
|
18
|
Male infertility |
GSE26881
|
Show abstract |
| 25753583 |
Unexplaine
d infertil
ity
|
|
|
46 (17 fertile
men, 29 male pa
tients)
|
Male infertility |
Microarray
|
Show abstract |
|