• Gene id: 83690

Gene Summary

• Gene Symbol: CRISPLD1   Gene   UCSC   Ensembl
• Aliases: CRISP-10, CRISP10, LCRISP1
• Gene name: cysteine rich secretory protein LCCL domain containing 1
• Alternate names: cysteine-rich secretory protein LCCL domain-containing 1, CocoaCrisp, LCCL domain-containing cysteine-rich secretory protein 1, cysteine-rich secretory protein 10, trypsin inhibitor Hl,
• Gene location: 8q21.13 (74984504: 75034557)     Exons: 16     NC_000008.11
• OMIM: 606865

Protein Summary

• Protein general information: Q9H336  
  • Name: Cysteine rich secretory protein LCCL domain containing 1 (CocoaCrisp) (Cysteine rich secretory protein 10) (CRISP 10) (LCCL domain containing cysteine rich secretory protein 1) (Trypsin inhibitor Hl)
  • Length: 500  
  • Mass: 56888
• Sequence:

  MKCTAREWLRVTTVLFMARAIPAMVVPNATLLEKLLEKYMDEDGEWWIAKQRGKRAITDNDMQSILDLHNKLRSQ
  VYPTASNMEYMTWDVELERSAESWAESCLWEHGPASLLPSIGQNLGAHWGRYRPPTFHVQSWYDEVKDFSYPYEH
  ECNPYCPFRCSGPVCTHYTQVVWATSNRIGCAINLCHNMNIWGQIWPKAVYLVCNYSPKGNWWGHAPYKHGRPCS
  ACPPSFGGGCRENLCYKEGSDRYYPPREEETNEIERQQSQVHDTHVRTRSDDSSRNEVISAQQMSQIVSCEVRLR
  DQCKGTTCNRYECPAGCLDSKAKVIGSVHYEMQSSICRAAIHYGIIDNDGGWVDITRQGRKHYFIKSNRNGIQTI
  GKYQSANSFTVSKVTVQAVTCETTVEQLCPFHKPASHCPRVYCPRNCMQANPHYARVIGTRVYSDLSSICRAAVH
  AGVVRNHGGYVDVMPVDKRKTYIASFQNGIFSESLQNPPGGKAFRVFAVV

• Structural information:
  • Protein Domains: (66..20-)
    (/note="SCP-)
    (289..38-)
    (/note="LCCL-1)
    (/evidence="ECO:0000255|PROSITE-ProRule:PRU00123-)
    (390..49-)
    (/note="LCCL-2)
    (/evidence="ECO:0000255|PROSITE-ProRule:PRU00123"-)
  • Interpro: IPR018244  IPR014044  IPR035940  IPR001283  IPR004043   IPR036609  
  • Prosite: PS01010 PS50820
  • STRING: ENSP00000262207
• Other Databases: GeneCards:  CRISPLD1  Malacards:  CRISPLD1

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0005615	extracellular space	IBA	cellular component
GO:0005576	extracellular region	IEA	cellular component
GO:0005576	extracellular region	IEA	cellular component
GO:0005576	extracellular region	IEA	cellular component
GO:0070062	extracellular exosome	HDA	cellular component
GO:0070062	extracellular exosome	HDA	cellular component
GO:0003674	molecular_function	ND	molecular function
GO:0060325	face morphogenesis	IMP	biological process

Diseases

Associated diseases	References
Aberrant CpGs in Low Motility Sperm	MIK: 21674046

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
21674046	Aberrant CpGs in Low Motility Sperm			18	Male infertility	GSE26881