• Gene id: 81577

Gene Summary

• Gene Symbol: GFOD2   Gene   UCSC   Ensembl
• Gene name: glucose-fructose oxidoreductase domain containing 2
• Alternate names: glucose-fructose oxidoreductase domain-containing protein 2,
• Gene location: 16q22.1 (67719315: 67674532)     Exons: 15     NC_000016.10

Protein Summary

• Protein general information: Q3B7J2  
  • Name: Glucose fructose oxidoreductase domain containing protein 2 (EC 1. . . )
  • Length: 385  
  • Mass: 42255
• Sequence:

  MKMLPGVGVFGTGSSARVLVPLLRAEGFTVEALWGKTEEEAKQLAEEMNIAFYTSRTDDILLHQDVDLVCISIPP
  PLTRQISVKALGIGKNVVCEKAATSVDAFRMVTASRYYPQLMSLVGNVLRFLPAFVRMKQLISEHYVGAVMICDA
  RIYSGSLLSPSYGWICDELMGGGGLHTMGTYIVDLLTHLTGRRAEKVHGLLKTFVRQNAAIRGIRHVTSDDFCFF
  QMLMGGGVCSTVTLNFNMPGAFVHEVMVVGSAGRLVARGADLYGQKNSATQEELLLRDSLAVGAGLPEQGPQDVP
  LLYLKGMVYMVQALRQSFQGQGDRRTWDRTPVSMAASFEDGLYMQSVVDAIKRSSRSGEWEAVEVLTEEPDTNQN
  LCEALQRNNL

• Structural information:
  • Interpro: IPR036291  IPR000683  
  • STRING: ENSP00000268797
• Other Databases: GeneCards:  GFOD2  Malacards:  GFOD2

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0030198	extracellular matrix organization	IBA	biological process
GO:0031012	extracellular matrix	IBA	cellular component
GO:0016491	oxidoreductase activity	IEA	molecular function
GO:0055114	oxidation-reduction process	IEA	biological process
GO:0005576	extracellular region	IEA	cellular component
GO:0016491	oxidoreductase activity	IEA	molecular function
GO:0030198	extracellular matrix organization	IEA	biological process
GO:0031012	extracellular matrix	IEA	cellular component

Diseases

Associated diseases	References
Cryptorchidism	MIK: 28606200
Spermatogenic defects	MIK: 31037746
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq
31037746	Spermatogenic defects			28 men with azoospermia	Male infertility	Microarray