• Gene id: 80774

Gene Summary

• Gene Symbol: LIMD2   Gene   UCSC   Ensembl
• Gene name: LIM domain containing 2
• Alternate names: LIM domain-containing protein 2, testicular tissue protein Li 106,
• Gene location: 17q23.3 (63701226: 63695887)     Exons: 7     NC_000017.11
• OMIM: 606722

Protein Summary

• Protein general information: Q9BT23  
  • Name: LIM domain containing protein 2
  • Length: 127  
  • Mass: 14070
• Sequence:

  MFQAAGAAQATPSHDAKGGGSSTVQRSKSFSLRAQVKETCAACQKTVYPMERLVADKLIFHNSCFCCKHCHTKLS
  LGSYAALHGEFYCKPHFQQLFKSKGNYDEGFGRKQHKELWAHKEVDPGTKTA

• Structural information:
  • Protein Domains: (38..9-)
    (/note="LIM-zinc-binding)
    (/evidence="ECO:0000255|PROSITE-ProRule:PRU00125"-)
  • Interpro: IPR001781  
  • Prosite: PS00478 PS50023
  • PDB: 2LZU
  • PDBsum: 2LZU
  • STRING: ENSP00000259006
• Other Databases: GeneCards:  LIMD2  Malacards:  LIMD2

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0046872	metal ion binding	IEA	molecular function
GO:0005634	nucleus	IEA	cellular component
GO:0005737	cytoplasm	IEA	cellular component
GO:0005515	protein binding	IPI	molecular function
GO:0005737	cytoplasm	IEA	cellular component
GO:0005634	nucleus	IEA	cellular component
GO:0005654	nucleoplasm	IDA	cellular component
GO:0005829	cytosol	IDA	cellular component

Diseases

Associated diseases	References
Aberrant CpGs in Low Motility Sperm	MIK: 21674046

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
21674046	Aberrant CpGs in Low Motility Sperm			18	Male infertility	GSE26881