• Gene id: 80323

Gene Summary

• Gene Symbol: CCDC68   Gene   UCSC   Ensembl
• Aliases: SE57-1
• Gene name: coiled-coil domain containing 68
• Alternate names: coiled-coil domain-containing protein 68, CTCL tumor antigen se57-1, CTCL-associated antigen se57-1, cutaneous T-cell lymphoma associated antigen, cutaneous T-cell lymphoma-associated antigen se57-1,
• Gene location: 18q21.2 (54959538: 54901508)     Exons: 15     NC_000018.10
• OMIM: 605846

Protein Summary

• Protein general information: Q9H2F9  
  • Name: Coiled coil domain containing protein 68 (Cutaneous T cell lymphoma associated antigen se57 1) (CTCL associated antigen se57 1)
  • Length: 335  
  • Mass: 38869
  • Tissue specificity: Expressed in bone marrow, colon, small intestine, spleen, testis, trachea and cutaneous T-cell lymphoma (CTCL). {ECO
• Sequence:

  MTTVTVTTEIPPRDKMEDNSALYESTSAHIIEETEYVKKIRTTLQKIRTQMFKDEIRHDSTNHKLDAKHCGNLQQ
  GSDSEMDPSCCSLDLLMKKIKGKDLQLLEMNKENEVLKIKLQASREAGAAALRNVAQRLFENYQTQSEEVRKKQE
  DSKQLLQVNKLEKEQKLKQHVENLNQVAEKLEEKHSQITELENLVQRMEKEKRTLLERKLSLENKLLQLKSSATY
  GKSCQDLQREISILQEQISHLQFVIHSQHQNLRSVIQEMEGLKNNLKEQDKRIENLREKVNILEAQNKELKTQVA
  LSSETPRTKVSKAVSTSELKTEGVSPYLMLIRLRK

• Structural information:
  • Interpro: IPR026735  
  • STRING: ENSP00000466690
• Other Databases: GeneCards:  CCDC68  Malacards:  CCDC68

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0035556	intracellular signal transduction	IBA	biological process
GO:0005856	cytoskeleton	IEA	cellular component
GO:0005737	cytoplasm	IEA	cellular component
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005814	centriole	IEA	cellular component
GO:0005515	protein binding	IPI	molecular function
GO:0005814	centriole	IDA	cellular component
GO:0008104	protein localization	IMP	biological process
GO:0120103	centriolar subdistal appendage	IDA	cellular component
GO:0034454	microtubule anchoring at centrosome	IGI	biological process
GO:0034454	microtubule anchoring at centrosome	IMP	biological process

Diseases

Associated diseases	References
Aberrant CpGs in Low Motility Sperm	MIK: 21674046

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
21674046	Aberrant CpGs in Low Motility Sperm			18	Male infertility	GSE26881