• Gene id: 80319

Gene Summary

• Gene Symbol: CXXC4   Gene   UCSC   Ensembl
• Aliases: IDAX
• Gene name: CXXC finger protein 4
• Alternate names: CXXC-type zinc finger protein 4, CXXC finger 4, Dvl-binding protein IDAX (inhibition of the Dvl and Axin complex), inhibition of the Dvl and axin complex protein,
• Gene location: 4q24 (104494966: 104468307)     Exons: 4     NC_000004.12
• Gene summary(Entrez): This gene encodes a CXXC-type zinc finger domain-containing protein that functions as an antagonist of the canonical wingless/integrated signaling pathway. The encoded protein negatively regulates wingless/integrated signaling through interaction with the
• OMIM: 611645

KEGG pathways

Pathway id	Pathway name
hsa04310	Wnt signaling pathway

Diseases

Associated diseases	References
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			13 (5 controls, 8 cases)	Male infertility	GSE6967 analyzed by GEO2R (cutoff 1.5 fold)