• Gene id: 80021

Gene Summary

• Gene Symbol: TMEM62   Gene   UCSC   Ensembl
• Gene name: transmembrane protein 62
• Alternate names: transmembrane protein 62,
• Gene location: 15q15.2 (43133114: 43185146)     Exons: 15     NC_000015.10

Protein Summary

• Protein general information: Q0P6H9  
  • Name: Transmembrane protein 62
  • Length: 643  
  • Mass: 73133
• Sequence:

  MAAVLALRVVAGLAAAALVAMLLEHYGLAGQPSPLPRPAPPRRPHPAPGPGDSNIFWGLQISDIHLSRFRDPGRA
  VDLEKFCSETIDIIQPALVLATGDLTDAKTKEQLGSRQHEVEWQTYQGILKKTRVMEKTKWLDIKGNHDAFNIPS
  LDSIKNYYRKYSAVRRDGSFHYVHSTPFGNYSFICVDATVNPGPKRPYNFFGILDKKKMEELLLLAKESSRSNHT
  IWFGHFTTSTILSPSPGIRSIMSSAIAYLCGHLHTLGGLMPVLHTRHFQGTLELEVGDWKDNRRYRIFAFDHDLF
  SFADLIFGKWPVVLITNPKSLLYSCGEHEPLERLLHSTHIRVLAFSLSSITSVTVKIDGVHLGQAVHVSGPIFVL
  KWNPRNYSSGTHNIEVIVQDSAGRSKSVHHIFSVQENNHLSFDPLASFILRTDHYIMARVLFVLIVLSQLTILII
  FRYRGYPELKEPSGFINLTSFSLHVLSKINIFYYSVLLLTLYTVLGPWFFGEIIDGKFGCCFSFGIFVNGHFLQG
  SITFIIGILQLAFFNIPLMAYMCWSLLQRCFGHNFRSHLHQRKYLKIMPVHLLMLLLYIWQVYSCYFLYATYGTL
  AFLFSPLRTWLTLLTPVLIRYVWTLNSTKFGIFMVQLKSHLSS

• Structural information:
  • Interpro: IPR004843  IPR029052  IPR041871  
  • CDD: cd07401
  • STRING: ENSP00000260403
• Other Databases: GeneCards:  TMEM62  Malacards:  TMEM62

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0016787	hydrolase activity	IEA	molecular function
GO:0016020	membrane	IEA	cellular component
GO:0016021	integral component of membrane	IEA	cellular component
GO:0016020	membrane	IEA	cellular component

Diseases

Associated diseases	References
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)