• Gene id: 80006

Gene Summary

• Gene Symbol: TRAPPC13   Gene   UCSC   Ensembl
• Aliases: C5orf44, SHLD3
• Gene name: trafficking protein particle complex 13
• Alternate names: trafficking protein particle complex subunit 13, REV7-interacting novel NHEJ regulator 1, Trs65-related, UPF0533 protein C5orf44,
• Gene location: 5q12.3 (65624730: 65666232)     Exons: 17     NC_000005.10

Protein Summary

• Protein general information: A5PLN9  
  • Name: Trafficking protein particle complex subunit 13
  • Length: 417  
  • Mass: 46524
• Sequence:

  MEVNPPKQEHLLALKVMRLTKPTLFTNIPVTCEEKDLPGDLFNQLMRDDPSTVNGAEVLMLGEMLTLPQNFGNIF
  LGETFSSYISVHNDSNQVVKDILVKADLQTSSQRLNLSASNAAVAELKPDCCIDDVIHHEVKEIGTHILVCAVSY
  TTQAGEKMYFRKFFKFQVLKPLDVKTKFYNAESDLSSVTDEVFLEAQIQNMTTSPMFMEKVSLEPSIMYNVTELN
  SVSQAGECVSTFGSRAYLQPMDTRQYLYCLKPKNEFAEKAGIIKGVTVIGKLDIVWKTNLGERGRLQTSQLQRMA
  PGYGDVRLSLEAIPDTVNLEEPFHITCKITNCSERTMDLVLEMCNTNSIHWCGISGRQLGKLHPSSSLCLALTLL
  SSVQGLQSISGLRLTDTFLKRTYEYDDIAQVCVVSSAIKVES

• Structural information:
  • Interpro: IPR010378  
  • DIP: 48284
  • STRING: ENSP00000409231
• Other Databases: GeneCards:  TRAPPC13  Malacards:  TRAPPC13

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0005829	cytosol	TAS	cellular component
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function

Diseases

Associated diseases	References
Cryptorchidism	MIK: 28606200
Spermatogenic defects	MIK: 31037746
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq
31037746	Spermatogenic defects			28 men with azoospermia	Male infertility	Microarray