• Gene id: 79729

Gene Summary

• Gene Symbol: SH3D21   Gene   UCSC   Ensembl
• Aliases: C1orf113
• Gene name: SH3 domain containing 21
• Alternate names: SH3 domain-containing protein 21, SH3 domain-containing protein C1orf113,
• Gene location: 1p34.3 (36306347: 36329220)     Exons: 18     NC_000001.11

Protein Summary

• Protein general information: A4FU49  
  • Name: SH3 domain containing protein 21
  • Length: 640  
  • Mass: 70519
• Sequence:

  MVQSELQLQPRAGGRAEAASWGDRGNDKGGLGNPDMPSVSPGPQRPPKLSSLAYDSPPDYLQTVSHPEVYRVLFD
  YQPEAPDELALRRGDVVKVLSKTTEDKGWWEGECQGRRGVFPDNFVLPPPPIKKLVPRKVVSRESAPIKEPKKLM
  PKTSLPTVKKLATATTGPSKAKTSRTPSRDSQKLTSRDSGPNGGFQSGGSYHPGRKRSKTQTPQQRSVSSQEEEH
  SSPVKAPSVKRTPMPDKTATPERPPAPENAPSSKKIPAPDKVPSPEKTLTLGDKASIPGNSTSGKIPAPDKVPTP
  EKMVTPEDKASIPENSIIPEETLTVDKPSTPERVFSVEESPALEAPPMDKVPNPKMAPLGDEAPTLEKVLTPELS
  EEEVSTRDDIQFHHFSSEEALQKVKYFVAKEDPSSQEEAHTPEAPPPQPPSSERCLGEMKCTLVRGDSSPRQAEL
  KSGPASRPALEKPHPHEEATTLPEEAPSNDERTPEEEAPPNEQRPLREEVLPKEGVASKEEVTLKEELPPKEEVA
  PKEEVPPIERAFAQKTRPIKPPPDSQETLALPSLVPQNYTENKNEGVDVTSLRGEVESLRRALELMEVQLERKLT
  DIWEELKSEKEQRRRLEVQVMQGTQKSQTPRVIHTQTQTY

• Structural information:
  • Protein Domains: (65..12-)
    (/note="SH3-)
    (/evidence="ECO:0000255|PROSITE-ProRule:PRU00192"-)
  • Interpro: IPR036028  IPR001452  IPR035468  
  • Prosite: PS50002
  • CDD: cd12142
  • STRING: ENSP00000421294
• Other Databases: GeneCards:  SH3D21  Malacards:  SH3D21

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0005886	plasma membrane	IDA	cellular component
GO:0005654	nucleoplasm	IDA	cellular component

Diseases

Associated diseases	References
Spermatogenic defects	MIK: 31037746

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
31037746	Spermatogenic defects			28 men with azoospermia	Male infertility	Microarray