• Gene id: 79649

Gene Summary

• Gene Symbol: MAP7D3   Gene   UCSC   Ensembl
• Aliases: MDP3
• Gene name: MAP7 domain containing 3
• Alternate names: MAP7 domain-containing protein 3,
• Gene location: Xq26.3 (136256481: 136213219)     Exons: 22     NC_000023.11
• Gene summary(Entrez): The protein encoded by this gene belongs to the MAP7 (microtubule-associated protein 7) family. Alternatively spliced transcript variants encoding different isoforms have been found. [provided by RefSeq, Mar 2010]
• OMIM: 611201

Protein Summary

• Protein general information: Q8IWC1  
  • Name: MAP7 domain containing protein 3
  • Length: 876  
  • Mass: 98429
• Sequence:

  MMADGAAAGAGGSPSLRELRARMVAAANEIAKERRKQDVVNRVATHSSNIRSTFKPVIDGSMLKNDIKQRLARER
  REEKRRQQDANKETQLLEKERKTKLQYEKQMEERQRKLKERKEKEEQRRIAAEEKRHQKDEAQKEKFTAILYRTL
  ERRRLADDYQQKRWSWGGSAMANSESKTANKRSASTEKLEQGTSALIRQMPLSSAGLQNSVAKRKTDKERSSSLN
  RRDSNLHSSTDKEQAERKPRVTGVTNYVMQYVTVPLRKCTSDELRAVMFPMSTMKIPPQTKVEESPLEKVETPPK
  ASVDAPPQVNVEVFCNTSMEASPKAGVGMAPEVSTDSFPVVSVDVSPVVSTYDSEMSMDASPELSIEALPKVDLE
  TVPKVSIVASPEASLEAPPEVSLEALPEVSVEAAPEGSLEAPPKGSAEVAPKESVKGSPKESMEASPEAMVKASP
  KTSLEASMEASPKAKARDAPKKSEMDKQALIPIAKKRLSSYTECYKWSSSPENACGLPSPISTNRQIQKNCPPSP
  LPLISKQSPQTSFPYKIMPIQHTLSVQSASSTVKKKKETVSKTTNRCEALSQRHMIYEESGNKSTAGIMNAEAAT
  KILTELRRLAREQREKEEEERQREEMQQRVIKKSKDMAKEAVGGQAEDHLKLKDGQQQNETKKKKGWLDQEDQEA
  PLQKGDAKIKAQEEADKRKKEHERIMLQNLQERLERKKRIEEIMKRTRKTDVNASKVTETSSHDIYEEAEADNEE
  SDKDSLNEMFPSAILNGTGSPTKFKMPFNNAKKMTHKLVFLEDGTSQVRKEPKTYFNGDLKNFRQKSMKDTSIQE
  VVSRPSSKRMTSHTTKTRKADETNTTSRSSAQTKSEGFHDILPKSSDTFRQ

• Structural information:
  • Interpro: IPR008604  
  • STRING: ENSP00000318086
• Other Databases: GeneCards:  MAP7D3  Malacards:  MAP7D3

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0015630	microtubule cytoskeleton	IBA	cellular component
GO:0000226	microtubule cytoskeleton organization	IBA	biological process
GO:0008017	microtubule binding	IDA	molecular function
GO:0015631	tubulin binding	IDA	molecular function
GO:0000226	microtubule cytoskeleton organization	IDA	biological process
GO:0046785	microtubule polymerization	IDA	biological process
GO:0015630	microtubule cytoskeleton	IEA	cellular component
GO:0000226	microtubule cytoskeleton organization	IEA	biological process
GO:0005856	cytoskeleton	IEA	cellular component
GO:0005737	cytoplasm	IEA	cellular component
GO:0005819	spindle	IEA	cellular component
GO:0016020	membrane	HDA	cellular component

Diseases

Associated diseases	References
Spermatogenic defects	MIK: 31037746

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
31037746	Spermatogenic defects			28 men with azoospermia	Male infertility	Microarray