• Gene id: 79627

Gene Summary

• Gene Symbol: OGFRL1   Gene   UCSC   Ensembl
• Aliases: dJ331H24.1
• Gene name: opioid growth factor receptor like 1
• Alternate names: opioid growth factor receptor-like protein 1,
• Gene location: 6q13 (71288295: 71309058)     Exons: 12     NC_000006.12

Protein Summary

• Protein general information: Q5TC84  
  • Name: Opioid growth factor receptor like protein 1
  • Length: 451  
  • Mass: 51252
  • Tissue specificity: Ubiquitous. {ECO
• Sequence:

  MGNLLGGVSFREPTTVEDCDSTWQTDSEPEPEEPGPGGGSEGPGQESEQPAQPPEQAGGRPGASPAPDEDAEAAG
  AEQGGDSTEATAKPKRSFYAARDLYKYRHQYPNFKDIRYQNDLSNLRFYKNKIPFKPDGVYIEEVLSKWKGDYEK
  LEHNHTYIQWLFPLREQGLNFYAKELTTYEIEEFKKTKEAIRRFLLAYKMMLEFFGIKLTDKTGNVARAVNWQER
  FQHLNESQHNYLRITRILKSLGELGYESFKSPLVKFILHEALVENTIPNIKQSALEYFVYTIRDRRERRKLLRFA
  QKHYTPSENFIWGPPRKEQSEGSKAQKMSSPLASSHNSQTSMHKKAKDSKNSSSAVHLNSKTAEDKKVAPKEPVE
  ETDRPSPEPSNEAAKPRNTEKDSNAENMNSQPEKTVTTPTEKKESVSPENNEEGGNDNQDNENPGNTNCHDVVLV
  Q

• Structural information:
  • Interpro: IPR006757  IPR039574  
  • STRING: ENSP00000359464
• Other Databases: GeneCards:  OGFRL1  Malacards:  OGFRL1

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0038023	signaling receptor activity	IEA	molecular function
GO:0004985	opioid receptor activity	IEA	molecular function
GO:0016020	membrane	IEA	cellular component
GO:0038003	opioid receptor signaling pathway	IEA	biological process

Diseases

Associated diseases	References
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			13 (5 controls, 8 cases)	Male infertility	GSE6967 analyzed by GEO2R (cutoff 1.5 fold)