• Gene id: 79616

Gene Summary

• Gene Symbol: CCNJL   Gene   UCSC   Ensembl
• Gene name: cyclin J like
• Alternate names: cyclin-J-like protein,
• Gene location: 5q33.3 (87059713: 86876905)     Exons: 26     NC_000007.14

Protein Summary

• Protein general information: Q8IV13  
  • Name: Cyclin J like protein
  • Length: 435  
  • Mass: 48406
• Sequence:

  MMDEPWWEGRVASDVHCTLREKELKLPTFRAHSPLLKSRRFFVDILTLLSSHCQLCPAARHLAVYLLDHFMDRYN
  VTTSKQLYTVAVSCLLLANGVSLLSPRLKCSGMISAHCNLHLPGSSNSPASAPHPPPTPPQVAETTGKFEDREDH
  VPKLEQINSTRILSSQNFTLTKKELLSTELLLLEAFSWNLCLPTPAHFLDYYLLASVSQKDHHCHTWPTTCPRKT
  KECLKEYAHYFLEVTLQDHIFYKFQPSVVAAACVGASRICLQLSPYWTRDLQRISSYSLEHLSTCIEILLVVYDN
  VLKDAVAVKSQALAMVPGTPPTPTQVLFQPPAYPALGQPATTLAQFQTPVQDLCLAYRDSLQAHRSGSLLSGSTG
  SSLHTPYQPLQPLDMCPVPVPASLSMHMAIAAEPRHCLATTYGSSYFSGSHMFPTGCFDR

• Structural information:
  • Protein Domains: (14..19-)
    (/note="Cyclin-N-terminal")
  • Interpro: IPR039361  IPR013763  IPR036915  IPR004367  IPR006671  
  • CDD: cd00043
  • STRING: ENSP00000377547
• Other Databases: GeneCards:  CCNJL  Malacards:  CCNJL

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0000307	cyclin-dependent protein kinase holoenzyme complex	IBA	cellular component
GO:0044772	mitotic cell cycle phase transition	IBA	biological process
GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity	IBA	biological process
GO:0005634	nucleus	IBA	cellular component
GO:0005737	cytoplasm	IBA	cellular component
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	IBA	molecular function
GO:0042025	host cell nucleus	IEA	cellular component

Diseases

Associated diseases	References
Aberrant CpGs in Low Motility Sperm	MIK: 21674046
Hypospermatogenesis	MIK: 28361989
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			13 (5 controls, 8 cases)	Male infertility	GSE6967 analyzed by GEO2R (cutoff 1.5 fold)
21674046	Aberrant CpGs in Low Motility Sperm			18	Male infertility	GSE26881
28361989	Hypospermatogenesis			6 (3 controls, 3 Klienfelter syndrome	Male infertility	Microarray