• Gene id: 79096

Gene Summary

• Gene Symbol: C11orf49   Gene   UCSC   Ensembl
• Gene name: chromosome 11 open reading frame 49
• Alternate names: UPF0705 protein C11orf49,
• Gene location: 11p11.2 (46936523: 47164384)     Exons: 13     NC_000011.10
• OMIM: 613994

Protein Summary

• Protein general information: Q9H6J7  
  • Name: UPF0705 protein C11orf49
  • Length: 331  
  • Mass: 37353
• Sequence:

  MLSPERLALPDYEYLAQRHVLTYMEDAVCQLLENREDISQYGIARFFTEYFNSVCQGTHILFREFSFVQATPHNR
  VSFLRAFWRCFRTVGKNGDLLTMKEYHCLLQLLCPDFPLELTQKAARIVLMDDAMDCLMSFSDFLFAFQIQFYYS
  EFLDSVAAIYEDLLSGKNPNTVIVPTSSSGQHRQRPALGGAGTLEGVEASLFYQCLENLCDRHKYSCPPPALVKE
  ALSNVQRLTFYGFLMALSKHRGINQALGALPDKGDLMHDPAMDEELERLLAQVPGLVNSVTASPEASCLPSRTPP
  RVGSPWRPLHHSRKVDGESDGSTEETDESET

• Structural information:
  • Interpro: IPR038968  
  • STRING: ENSP00000367878
• Other Databases: GeneCards:  C11orf49  Malacards:  C11orf49

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function

Diseases

Associated diseases	References
Cryptorchidism	MIK: 28606200
Teratozoospermia	MIK: 17327269
Unexplained infertility	MIK: 25753583

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq
25753583	Unexplained infertility			46 (17 fertile men, 29 male patients)	Male infertility	Microarray