|
Gene id |
79008 |
| Gene Summary Protein Summary KEGG pathways Diseases PubMed |
Gene Summary
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|
Gene Symbol |
SLX1B Gene UCSC Ensembl |
|
Aliases |
GIYD2 |
|
Gene name |
SLX1 homolog B, structure-specific endonuclease subunit |
|
Alternate names |
structure-specific endonuclease subunit SLX1, GIY-YIG domain-containing protein 1, SLX1 structure-specific endonuclease subunit homolog B, |
|
Gene location |
16p11.2 (29454500: 29458223) Exons: 6 NC_000016.10
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|
Gene summary(Entrez) |
This gene encodes a protein that is an important regulator of genome stability. The protein represents the catalytic subunit of the SLX1-SLX4 structure-specific endonuclease, which can resolve DNA secondary structures that are formed during repair and rec
|
|
OMIM |
615823 |
Protein Summary
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|
| Pathway id | Pathway name |
|---|
| hsa03460 | Fanconi anemia pathway | |
|
| Associated diseases |
References |
| Teratozoospermia | MIK: 17327269 |
|
|
| PMID |
Condition |
Mutation |
Ethnicity |
Population details |
Infertility_type |
Associated_genes |
Abstract |
| 17327269 |
Teratozoos
permia
|
|
|
13 (5 controls,
8 cases)
|
Male infertility |
GSE6967 analyzed by GEO2R (cutoff 1.5 fold)
|
Show abstract |
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