• Gene id: 728395

Gene Summary

• Gene Symbol: TSPY4   Gene   UCSC   Ensembl
• Aliases: TSPY10, TSPY8
• Gene name: testis specific protein Y-linked 4
• Alternate names: testis-specific Y-encoded protein 4,
• Gene location: Yp11.2 (9337488: 9340284)     Exons: 6     NC_000024.10
• OMIM: 600058

Protein Summary

• Protein general information: P0CV99  
  • Name: Testis specific Y encoded protein 4
  • Length: 314  
  • Mass: 35727
• Sequence:

  MRPEGSLTYRVPERLRQGFCGVGRAAQALVCASAKEGTAFRMEAVQEGAAGVESEQAALGEEAVLLLDDIMAEVE
  VVAEVEVVAEEEGLVERREEAQRAQQAVPGPGPMTPESALEELLAVQVELEPVNAQARKAFSRQREKMERRRKPH
  LDRRGAVIQSVPGFWANVIANHPQMSALITDEDEDMLSYMVSLEVEEEKHPVHLCKIMLFFRSNPYFQNKVITKE
  YLVNITEYRASHSTPIEWYPDYEVEAYRRRHHNSSLNFFNWFSDHNFAGSNKIAEILCKDLWRNPLQYYKRMKPP
  EEGTETSGDSQLLS

• Structural information:
  • Interpro: IPR037231  IPR002164  
• Other Databases: GeneCards:  TSPY4  Malacards:  TSPY4

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0042393	histone binding	IBA	molecular function
GO:0003682	chromatin binding	IBA	molecular function
GO:0005634	nucleus	IBA	cellular component
GO:0006334	nucleosome assembly	IEA	biological process
GO:0005634	nucleus	IEA	cellular component
GO:0007283	spermatogenesis	IEA	biological process
GO:0007506	gonadal mesoderm development	IEA	biological process
GO:0030154	cell differentiation	IEA	biological process
GO:0007275	multicellular organism development	IEA	biological process

Diseases

Associated diseases	References
Cryptorchidism	MIK: 28606200

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq