• Gene id: 728378

Gene Summary

• Gene Symbol: POTEF   Gene   UCSC   Ensembl
• Aliases: A26C1B, ACTB, POTE2alpha, POTEACTIN
• Gene name: POTE ankyrin domain family member F
• Alternate names: POTE ankyrin domain family member F, ANKRD26-like family C member 1B, POTE-2 alpha-actin, beta actin, chimeric POTE-actin protein, prostate, ovary, testis expressed protein on chromosome 2,
• Gene location: 2q21.1 (130129221: 130073534)     Exons: 17     NC_000002.12

Protein Summary

• Protein general information: A5A3E0  
  • Name: POTE ankyrin domain family member F (ANKRD26 like family C member 1B) (Chimeric POTE actin protein)
  • Length: 1075  
  • Mass: 121445
  • Tissue specificity: Expressed in breast cancer cell lines (at protein level). {ECO
• Sequence:

  MVVEVDSMPAASSVKKPFGLRSKMGKWCCRCFPCCRESGKSNVGTSGDHDDSAMKTLRSKMGKWCRHCFPCCRGS
  GKSNVGASGDHDDSAMKTLRNKMGKWCCHCFPCCRGSSKSKVGAWGDYDDSAFMEPRYHVRGEDLDKLHRAAWWG
  KVPRKDLIVMLRDTDVNKQDKQKRTALHLASANGNSEVVKLLLDRRCQLNVLDNKKRTALIKAVQCQEDECALML
  LEHGTDPNIPDEYGNTTLHYAIYNEDKLMAKALLLYGADIESKNKHGLTPLLLGVHEQKQQVVKFLIKKKANLNA
  LDRYGRTALILAVCCGSASIVSLLLEQNIDVSSQDLSGQTAREYAVSSHHHVICQLLSDYKEKQMLKISSENSNP
  EQDLKLTSEEESQRFKGSENSQPEKMSQEPEINKDGDREVEEEMKKHESNNVGLLENLTNGVTAGNGDNGLIPQR
  KSRTPENQQFPDNESEEYHRICELLSDYKEKQMPKYSSENSNPEQDLKLTSEEESQRLKGSENGQPEKRSQEPEI
  NKDGDRELENFMAIEEMKKHRSTHVGFPENLTNGATAGNGDDGLIPPRKSRTPESQQFPDTENEEYHSDEQNDTQ
  KQFCEEQNTGILHDEILIHEEKQIEVVEKMNSELSLSCKKEKDILHENSTLREEIAMLRLELDTMKHQSQLREKK
  YLEDIESVKKRNDNLLKALQLNELTMDDDTAVLVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRQQGMMGGMHQK
  ESYVGKEAQSKRGILTLKYPMEHGIITNWDDMEKIWHHTFYNELRVAPEEHPVLLTEATLNPKANREKMTQIMFE
  TFNTPAMYVAIQAVLSLYTSGRTTGIVMDSGDGVTHTVPIYEGNALPHATLRLDLAGRELPDYLMKILTEHGYRF
  TTMAEREIVRDIKEKLCYVALDFEQEMATVASSSSLEKSYELPDGQVITIGNERFRCPEALFQPCFLGMESCGIH
  ETTFNSIMKSDVDIRKDLYTNTVLSGGTTMYPGMAHRMQKEIAALAPSMMKIRIIAPPKRKYSVWVGGSILASLS
  TFQQMWISKQEYDESGPSIVHRKCL

• Structural information:
  • Interpro: IPR004000  IPR020902  IPR004001  IPR002110  IPR020683   IPR036770  IPR039497  
  • Prosite: PS00432 PS01132 PS50297 PS50088
  • STRING: ENSP00000350052
• Other Databases: GeneCards:  POTEF  Malacards:  POTEF

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0005737	cytoplasm	IEA	cellular component
GO:0005938	cell cortex	IEA	cellular component
GO:0001895	retina homeostasis	HEP	biological process
GO:0072562	blood microparticle	HDA	cellular component
GO:0005615	extracellular space	HDA	cellular component
GO:0005615	extracellular space	HDA	cellular component
GO:0070062	extracellular exosome	HDA	cellular component

Diseases

Associated diseases	References
Cryptorchidism	MIK: 28606200

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq