|
Gene id |
7161 |
| Gene Summary Protein Summary Gene ontology KEGG pathways Diseases PubMed |
Gene Summary
|
|
Gene Symbol |
TP73 Gene UCSC Ensembl |
|
Aliases |
P73 |
|
Gene name |
tumor protein p73 |
|
Alternate names |
tumor protein p73, p53-like transcription factor, p53-related protein, |
|
Gene location |
1p36.32 (3652515: 3736200) Exons: 16 NC_000001.11
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|
Gene summary(Entrez) |
This gene encodes a member of the p53 family of transcription factors involved in cellular responses to stress and development. It maps to a region on chromosome 1p36 that is frequently deleted in neuroblastoma and other tumors, and thought to contain mul
|
|
OMIM |
601990 |
Protein Summary
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|
| GO accession | Term name | Evidence code | Go category |
|---|
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|
|
|
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| Associated diseases |
References |
| Cancer | GAD: 17617876 |
| Cancer (hepatocellular) | KEGG: H00048 |
| Neuroblastoma | OMIM: 601990 |
| Diminished ovarian reserve (DOR) | INFBASE: 25794170 |
| Oligoasthenozoospermia | MIK: 30358834 |
| Oligozoospermia | MIK: 30358834 |
| Aberrant CpGs in Low Motility Sperm | MIK: 21674046 |
| Cryptorchidism | MIK: 28606200 |
| Male infertility | MIK: 27525684 |
| Spermatogenic defects | MIK: 31037746 |
| Teratozoospermia | MIK: 17327269 |
| Unexplained infertility | MIK: 25753583 |
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|
| PMID |
Condition |
Mutation |
Ethnicity |
Population details |
Infertility_type |
Associated_genes |
Abstract |
| 27525684 |
Male infer
tility wit
h severe s
permatogen
esis
|
G4C14-to-A4T14 |
Chinese
|
553 (301 infert
ile patients wi
th severe sperm
atogenesis impa
irment (includi
ng azoospermia
and severe olig
ospermia), 252
fertile men)
|
Male infertility |
|
Show abstract |
| 17327269 |
Teratozoos
permia
|
|
|
13 (5 controls,
8 cases)
|
Male infertility |
GSE6967 analyzed by GEO2R (cutoff 1.5 fold)
|
Show abstract |
| 21674046 |
Aberrant C
pGs in Low
Motility
Sperm
|
|
|
18
|
Male infertility |
GSE26881
|
Show abstract |
| 28606200 |
Cryptorchi
dism
|
|
|
Monozgotic twin
s (1 control, I
cwith cryptorc
hidism)
|
Male infertility |
MeDIP-Seq
|
Show abstract |
| 31037746 |
Spermatoge
nic defect
s
|
|
|
16 (1 control,
15 cases)
|
Male infertility |
GSE6023 analyzed using GEO2R
|
Show abstract |
| 25753583 |
Unexplaine
d infertil
ity
|
|
|
46 (17 fertile
men, 29 male pa
tients)
|
Male infertility |
Microarray
|
Show abstract |
|