• Gene id: 6991

Gene Summary

• Gene Symbol: TCTE3   Gene   UCSC   Ensembl
• Aliases: TCTEX1D3
• Gene name: t-complex-associated-testis-expressed 3
• Alternate names: tctex1 domain-containing protein 3, T-complex testis-specific protein 3, T-complex-associated testis-expressed protein 3, Tctex1 domain containing 3,
• Gene location: 6q27 (169751580: 169725487)     Exons: 5     NC_000006.12
• OMIM: 186977

Protein Summary

• Protein general information: Q8IZS6  
  • Name: Tctex1 domain containing protein 3 (T complex testis specific protein 3) (T complex associated testis expressed protein 3) (Tcte 3)
  • Length: 198  
  • Mass: 23176
  • Tissue specificity: Expressed predominantly in testis. Also expressed in brain, lung and trachea. {ECO
• Sequence:

  MEKRGRGVKSSPIQTPNQTPQQAPVTPRKERRPSMFEKEAYTQILRERLRESIHNVQYVEPPFDDSIADIGKEWK
  SALAKLKFANSYRMEPLKKFQAHSVETKVQQILTESLKDVKYDDKVFSHLSLELADRILLAVKEFGYHRYKFIIK
  VLFIQKTGQAINIASRWIWDIAWDSWVAAKHEAESYVALVLVFALYYE

• Structural information:
  • Interpro: IPR005334  IPR038586  
  • STRING: ENSP00000355736
• Other Databases: GeneCards:  TCTE3  Malacards:  TCTE3

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0003774	motor activity	IEA	molecular function
GO:0030286	dynein complex	IEA	cellular component
GO:0005737	cytoplasm	IEA	cellular component
GO:0016020	membrane	IEA	cellular component
GO:0005856	cytoskeleton	IEA	cellular component
GO:0005874	microtubule	IEA	cellular component
GO:0005515	protein binding	IPI	molecular function
GO:0005856	cytoskeleton	IEA	cellular component
GO:0016020	membrane	IEA	cellular component

Diseases

Associated diseases	References
Aberrant CpGs in Low Motility Sperm	MIK: 21674046
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
21674046	Aberrant CpGs in Low Motility Sperm			18	Male infertility	GSE26881