|
Gene id |
6868 |
| Gene Summary Protein Summary Gene ontology KEGG pathways Diseases PubMed |
Gene Summary
|
|
Gene Symbol |
ADAM17 Gene UCSC Ensembl |
|
Aliases |
ADAM18, CD156B, CSVP, NISBD, NISBD1, TACE |
|
Gene name |
ADAM metallopeptidase domain 17 |
|
Alternate names |
disintegrin and metalloproteinase domain-containing protein 17, ADAM metallopeptidase domain 18, TNF-alpha convertase, TNF-alpha converting enzyme, snake venom-like protease, tumor necrosis factor, alpha, converting enzyme, |
|
Gene location |
2p25.1 (9555829: 9488485) Exons: 20 NC_000002.12
|
|
Gene summary(Entrez) |
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes i
|
|
OMIM |
603639 |
Protein Summary
|
|
| GO accession | Term name | Evidence code | Go category |
|---|
|
|
| Pathway id | Pathway name |
|---|
| hsa05010 | Alzheimer disease | | hsa05120 | Epithelial cell signaling in Helicobacter pylori infection | |
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| Associated diseases |
References |
| Aberrant CpGs in Low Motility Sperm | MIK: 21674046 |
| Role in germ cell differentiation | MIK: 25053185 |
| Spermatogenic defects | MIK: 31037746 |
|
|
| PMID |
Condition |
Mutation |
Ethnicity |
Population details |
Infertility_type |
Associated_genes |
Abstract |
| 25053185 |
Role in ge
rm cell di
fferentiat
ion
|
|
|
|
Male infertility |
|
Show abstract |
| 21674046 |
Aberrant C
pGs in Low
Motility
Sperm
|
|
|
18
|
Male infertility |
GSE26881
|
Show abstract |
| 31037746 |
Spermatoge
nic defect
s
|
|
|
16 (1 control,
15 cases)
|
Male infertility |
GSE6023 analyzed using GEO2R
|
Show abstract |
|