|
Gene id |
6815 |
| Gene Summary Protein Summary Gene ontology Diseases PubMed |
Gene Summary
|
|
Gene Symbol |
STYX Gene UCSC Ensembl |
|
Gene name |
serine/threonine/tyrosine interacting protein |
|
Alternate names |
serine/threonine/tyrosine-interacting protein, inactive tyrosine-protein phosphatase STYX, phosphoserine/threonine/tyrosine interaction protein, protein tyrosine phosphatase-like protein, |
|
Gene location |
14q22.1 (52730158: 52774988) Exons: 12 NC_000003.12
|
|
Gene summary(Entrez) |
The protein encoded by this gene is a pseudophosphatase, able to bind potential substrates but lacking an active catalytic loop. The encoded protein may be involved in spermiogenesis. Two transcript variants encoding the same protein have been found for t
|
|
OMIM |
615814 |
Protein Summary
|
|
| GO accession | Term name | Evidence code | Go category |
|---|
|
|
| Associated diseases |
References |
| Oligozoospermia | GAD: 19369647 |
| Male infertility because of structural head abnormalities in residual epididymal sperm | MIK: 11842224 |
| Azoospermia | GAD: 19369647 |
| Aberrant CpGs in Low Motility Sperm | MIK: 21674046 |
| Associated with spermatogenesis and epigenetic regulation | MIK: 21674046 |
| Cryptorchidism | MIK: 28606200 |
| Male infertility because of structural head abnormalities in residual epididymal sperm | MIK: 11842224 |
| Teratozoospermia | MIK: 17327269 |
|
|
| PMID |
Condition |
Mutation |
Ethnicity |
Population details |
Infertility_type |
Associated_genes |
Abstract |
| 11842224 |
Male infer
tility bec
ause of st
ructural h
ead abnorm
alities in
residual
epididymal
sperm
|
|
|
|
Male infertility |
|
Show abstract |
| 17327269 |
Teratozoos
permia
|
|
|
13 (5 controls,
8 cases)
|
Male infertility |
GSE6967 analyzed by GEO2R (cutoff 1.5 fold)
|
Show abstract |
| 21674046 |
Associated
with sper
matogenesi
s and epig
enetic reg
ulation
|
|
|
18
|
Male infertility |
GSE26881
|
Show abstract |
| 28606200 |
Cryptorchi
dism
|
|
|
Monozgotic twin
s (1 control, I
cwith cryptorc
hidism)
|
Male infertility |
MeDIP-Seq
|
Show abstract |
|