• Gene id: 65244

Gene Summary

• Gene Symbol: SPATS2   Gene   UCSC   Ensembl
• Aliases: Nbla00526, P59SCR, SCR59, SPATA10
• Gene name: spermatogenesis associated serine rich 2
• Alternate names: spermatogenesis-associated serine-rich protein 2, putative protein product of Nbla00526, serine-rich spermatocytes and round spermatid 59 kDa protein, serine-rich spermatocytes and round spermatid protein,
• Gene location: 12q13.12 (49366908: 49527440)     Exons: 16     NC_000012.12
• OMIM: 602519

Protein Summary

• Protein general information: Q86XZ4  
  • Name: Spermatogenesis associated serine rich protein 2 (Serine rich spermatocytes and round spermatid 59 kDa protein) (p59scr)
  • Length: 545  
  • Mass: 59545
• Sequence:

  MSRKQNQKDSSGFIFDLQSNTVLAQGGAFENMKEKINAVRAIVPNKSNNEIILVLQHFDNCVDKTVQAFMEGSAS
  EVLKEWTVTGKKKNKKKKNKPKPAAEPSNGIPDSSKSVSIQEEQSAPSSEKGGMNGYHVNGAINDTESVDSLSEG
  LETLSIDARELEDPESAMLDTLDRTGSMLQNGVSDFETKSLTMHSIHNSQQPRNAAKSLSRPTTETQFSNMGMED
  VPLATSKKLSSNIEKSVKDLQRCTVSLARYRVVVKEEMDASIKKMKQAFAELESCLMDREVALLAEMDKVKAEAM
  EILLSRQKKAELLKKMTHVAVQMSEQQLVELRADIKHFVSERKYDEDLGRVARFTCDVETLKKSIDSFGQVSHPK
  NSYSTRSRCSSVTSVSLSSPSDASAASSSTCASPPSLTSANKKNFAPGETPAAIANSSGQPYQPLREVLPGNRRG
  GQGYRPQGQKSNDPMNQGRHDSMGRYRNSSWYSSGSRYQSAPSQAPGNTIERGQTHSAGTNGTGVSMEPSPPTPS
  FKKGLPQRKPRTSQTEAVNS

• Structural information:
  • Interpro: IPR009816  IPR009060  
  • STRING: ENSP00000448228
• Other Databases: GeneCards:  SPATS2  Malacards:  SPATS2

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0005737	cytoplasm	IBA	cellular component
GO:0005737	cytoplasm	IEA	cellular component
GO:0005737	cytoplasm	IEA	cellular component
GO:0005737	cytoplasm	IEA	cellular component
GO:0005829	cytosol	IDA	cellular component
GO:0003723	RNA binding	HDA	molecular function

Diseases

Associated diseases	References
Cryptorchidism	MIK: 28606200
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			19 (6 controls, 13 cases)	Male infertility	GSE6872 analyzed by GEO2R (cutoff 1.5 fold)
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq