• Gene id: 65005

Gene Summary

• Gene Symbol: MRPL9   Gene   UCSC   Ensembl
• Aliases: L9mt
• Gene name: mitochondrial ribosomal protein L9
• Alternate names: 39S ribosomal protein L9, mitochondrial, mitochondrial large ribosomal subunit protein bL9m,
• Gene location: 1q21.3 (151763495: 151759646)     Exons: 7     NC_000001.11
• Gene summary(Entrez): This is a nuclear gene encoding a protein component of the 39S subunit of the mitochondrial ribosome. Alternative splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 8. [provided by RefSeq, Jul 2014]
• OMIM: 608868

Protein Summary

• Protein general information: Q9BYD2  
  • Name: 39S ribosomal protein L9, mitochondrial (L9mt) (MRP L9) (Mitochondrial large ribosomal subunit protein bL9m)
  • Length: 267  
  • Mass: 30243
• Sequence:

  MAAPVVTAPGRALLRAGAGRLLRGGVQELLRPRHEGNAPDLACNFSLSQNRGTVIVERWWKVPLAGEGRKPRLHR
  RHRVYKLVEDTKHRPKENLELILTQSVENVGVRGDLVSVKKSLGRNRLLPQGLAVYASPENKKLFEEEKLLRQEG
  KLEKIQTKAGEATVKFLKSCRLEVGMKNNVKWELNPEIVARHFFKNLGVVVAPHTLKLPEEPITRWGEYWCEVTV
  NGLDTVRVPMSVVNFEKPKTKRYKYWLAQQAAKAMAPTSPQI

• Structural information:
  • Interpro: IPR000244  IPR009027  IPR020070  IPR036935  
  • PDB: 3J7Y 3J9M 5OOL 5OOM 6NU2 6NU3
  • PDBsum: 3J7Y 3J9M 5OOL 5OOM 6NU2 6NU3
  • STRING: ENSP00000357823
• Other Databases: GeneCards:  MRPL9  Malacards:  MRPL9

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0005739	mitochondrion	IBA	cellular component
GO:0005762	mitochondrial large ribosomal subunit	IDA	cellular component
GO:0005762	mitochondrial large ribosomal subunit	IDA	cellular component
GO:0005739	mitochondrion	IDA	cellular component
GO:0005840	ribosome	IEA	cellular component
GO:0006412	translation	IEA	biological process
GO:0003735	structural constituent of ribosome	IEA	molecular function
GO:0005840	ribosome	IEA	cellular component
GO:0005739	mitochondrion	IEA	cellular component
GO:0005743	mitochondrial inner membrane	TAS	cellular component
GO:0005743	mitochondrial inner membrane	TAS	cellular component
GO:0005743	mitochondrial inner membrane	TAS	cellular component
GO:0005743	mitochondrial inner membrane	TAS	cellular component
GO:0005743	mitochondrial inner membrane	TAS	cellular component
GO:0005743	mitochondrial inner membrane	TAS	cellular component
GO:0070125	mitochondrial translational elongation	TAS	biological process
GO:0070126	mitochondrial translational termination	TAS	biological process
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005739	mitochondrion	IEA	cellular component
GO:0005739	mitochondrion	IDA	cellular component
GO:0003735	structural constituent of ribosome	NAS	molecular function
GO:0003723	RNA binding	HDA	molecular function
GO:0005761	mitochondrial ribosome	NAS	cellular component
GO:0006412	translation	NAS	biological process

KEGG pathways

Pathway id	Pathway name
hsa03010	Ribosome

Diseases

Associated diseases	References
Unexplained infertility	MIK: 25753583

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
25753583	Unexplained infertility			46 (17 fertile men, 29 male patients)	Male infertility	Microarray