• Gene id: 6289

Gene Summary

• Gene Symbol: SAA2   Gene   UCSC   Ensembl
• Aliases: SAA, SAA1
• Gene name: serum amyloid A2
• Alternate names: serum amyloid A-2 protein, Serum amyloid A-1 protein,
• Gene location: 11p15.1 (18248667: 18238235)     Exons: 16     NC_000011.10
• OMIM: 104751

Protein Summary

• Protein general information: P0DJI9  
  • Name: Serum amyloid A 2 protein (SAA2)
  • Length: 122  
  • Mass: 13527
  • Tissue specificity: Expressed by the liver; secreted in plasma.
• Sequence:

  MKLLTGLVFCSLVLSVSSRSFFSFLGEAFDGARDMWRAYSDMREANYIGSDKYFHARGNYDAAKRGPGGAWAAEV
  ISNARENIQRLTGRGAEDSLADQAANKWGRSGRDPNHFRPAGLPEKY

• Structural information:
  • Interpro: IPR000096  
  • Prosite: PS00992
  • STRING: ENSP00000436126
• Other Databases: GeneCards:  SAA2  Malacards:  SAA2

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0042056	chemoattractant activity	IBA	molecular function
GO:0060326	cell chemotaxis	IBA	biological process
GO:0005615	extracellular space	IBA	cellular component
GO:0005576	extracellular region	IEA	cellular component
GO:0005576	extracellular region	IEA	cellular component
GO:0006953	acute-phase response	IEA	biological process
GO:0034364	high-density lipoprotein particle	IEA	cellular component
GO:0005515	protein binding	IPI	molecular function
GO:0005576	extracellular region	IEA	cellular component
GO:0050918	positive chemotaxis	IEA	biological process
GO:0070062	extracellular exosome	HDA	cellular component

Diseases

Associated diseases	References
Teratozoospermia	MIK: 17327269

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
17327269	Teratozoospermia			13 (5 controls, 8 cases)	Male infertility	GSE6967 analyzed by GEO2R (cutoff 1.5 fold)