• Gene id: 57701

Gene Summary

• Gene Symbol: NCKAP5L   Gene   UCSC   Ensembl
• Aliases: Cep169, FP1193, KIAA1602
• Gene name: NCK associated protein 5 like
• Alternate names: nck-associated protein 5-like, NCKAP5-like, centrosomal protein of 169 kDa,
• Gene location: 12q13.12 (49828749: 49791138)     Exons: 14     NC_000012.12
• OMIM: 613316

Protein Summary

• Protein general information: Q9HCH0  
  • Name: Nck associated protein 5 like (NCKAP5 like) (Centrosomal protein of 169 kDa) (Cep169)
  • Length: 1330  
  • Mass: 139013
• Sequence:

  MDQPAGGPGNPRPGEGDDGSMEPGTCQELLHRLRELEAENSALAQANENQRETYERCLDEVANHVVQALLNQKDL
  REECIKLKKRVFDLERQNQMLSALFQQKLQLTTGSLPQIPLTPLQPPSEPPASPSLSSTEGPAAPLPLGHCAGQR
  EVCWEQQLRPGGPGPPAAPPPALDALSPFLRKKAQILEVLRALEETDPLLLCSPATPWRPPGQGPGSPEPINGEL
  CGPPQPEPSPWAPCLLLGPGNLGGLLHWERLLGGLGGEEDTGRPWGPSRGPPQAQGTSSGPNCAPGSSSSSSSDE
  AGDPNEAPSPDTLLGALARRQLNLGQLLEDTESYLQAFLAGAAGPLNGDHPGPGQSSSPDQAPPQLSKSKGLPKS
  AWGGGTPEAHRPGFGATSEGQGPLPFLSMFMGAGDAPLGSRPGHPHSSSQVKSKLQIGPPSPGEAQGPLLPSPAR
  GLKFLKLPPTSEKSPSPGGPQLSPQLPRNSRIPCRNSGSDGSPSPLLARRGLGGGELSPEGAQGLPTSPSPCYTT
  PDSTQLRPPQSALSTTLSPGPVVSPCYENILDLSRSTFRGPSPEPPPSPLQVPTYPQLTLEVPQAPEVLRSPGVP
  PSPCLPESYPYGSPQEKSLDKAGSESPHPGRRTPGNSSKKPSQGSGRRPGDPGSTPLRDRLAALGKLKTGPEGAL
  GSEKNGVPARPGTEKTRGPGKSGESAGDMVPSIHRPLEQLEAKGGIRGAVALGTNSLKQQEPGLMGDPGARVYSS
  HSMGARVDLEPVSPRSCLTKVELAKSRLAGALCPQVPRTPAKVPTSAPSLGKPNKSPHSSPTKLPSKSPTKVVPR
  PGAPLVTKESPKPDKGKGPPWADCGSTTAQSTPLVPGPTDPSQGPEGLAPHSAIEEKVMKGIEENVLRLQGQERA
  PGAEVKHRNTSSIASWFGLKKSKLPALNRRTEATKNKEGAGGGSPLRREVKMEARKLEAESLNISKLMAKAEDLR
  RALEEEKAYLSSRARPRPGGPAPGPNTGLGQVQGQLAGMYQGADTFMQQLLNRVDGKELPSKSWREPKPEYGDFQ
  PVSSDPKSPWPACGPRNGLVGPLQGCGKPPGKPSSEPGRREETPSEDSLAEPVPTSHFTACGSLTRTLDSGIGTF
  PPPDHGSSGTPSKNLPKTKPPRLDPPPGVPPARPPPLTKVPRRAHTLEREVPGIEELLVSGRHPSMPAFPALLPA
  APGHRGHETCPDDPCEDPGPTPPVQLAKNWTFPNTRAAGSSSDPLMCPPRQLEGLPRTPMALPVDRKRSQEPSRP
  SPTPQGPPFGGSRTPSTSDMAEEGRVASGGPPGLETSESLSDSLYDSLSSCGSQG

• Structural information:
  • Interpro: IPR032769  IPR026163  
  • STRING: ENSP00000337998
• Other Databases: GeneCards:  NCKAP5L  Malacards:  NCKAP5L

Gene ontology

GO accession	Term name	Evidence code	Go category
GO:0007019	microtubule depolymerization	IBA	biological process
GO:0035371	microtubule plus-end	IBA	cellular component
GO:0001578	microtubule bundle formation	IBA	biological process
GO:0005813	centrosome	IDA	cellular component
GO:0001578	microtubule bundle formation	IDA	biological process
GO:0035371	microtubule plus-end	IDA	cellular component
GO:0007019	microtubule depolymerization	IMP	biological process
GO:0005515	protein binding	IPI	molecular function
GO:0005515	protein binding	IPI	molecular function
GO:0005856	cytoskeleton	IEA	cellular component
GO:0005737	cytoplasm	IEA	cellular component
GO:0005874	microtubule	IEA	cellular component
GO:0005815	microtubule organizing center	IEA	cellular component

Diseases

Associated diseases	References
Cryptorchidism	MIK: 28606200

PubMed references

PMID	Condition	Mutation	Ethnicity	Population details	Infertility_type	Associated_genes
28606200	Cryptorchidism			Monozgotic twins (1 control, I cwith cryptorchidism)	Male infertility	MeDIP-Seq